ID   G4FK16_9SYNE            Unreviewed;       455 AA.
AC   G4FK16;
DT   14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2011, sequence version 1.
DT   24-JAN-2024, entry version 29.
DE   SubName: Full=Peptidase U62 modulator of DNA gyrase {ECO:0000313|EMBL:EHA63326.1};
GN   ORFNames=Syn8016DRAFT_0367 {ECO:0000313|EMBL:EHA63326.1};
OS   Synechococcus sp. WH 8016.
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales; Synechococcaceae;
OC   Synechococcus.
OX   NCBI_TaxID=166318 {ECO:0000313|EMBL:EHA63326.1, ECO:0000313|Proteomes:UP000002752};
RN   [1] {ECO:0000313|EMBL:EHA63326.1, ECO:0000313|Proteomes:UP000002752}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WH8016 {ECO:0000313|Proteomes:UP000002752};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Peters L., Land M.L., Hauser L., Palenik B., Woyke T.J.;
RT   "The draft genome of Synechococcus sp. WH 8016.";
RL   Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase U62 family.
CC       {ECO:0000256|ARBA:ARBA00005836}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EHA63326.1}.
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DR   EMBL; AGIK01000001; EHA63326.1; -; Genomic_DNA.
DR   RefSeq; WP_006852506.1; NZ_AGIK01000001.1.
DR   AlphaFoldDB; G4FK16; -.
DR   STRING; 166318.Syn8016DRAFT_0367; -.
DR   PATRIC; fig|166318.3.peg.408; -.
DR   eggNOG; COG0312; Bacteria.
DR   OrthoDB; 9803618at2; -.
DR   Proteomes; UP000002752; Unassembled WGS sequence.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 3.30.2290.10; PmbA/TldD superfamily; 1.
DR   InterPro; IPR045569; Metalloprtase-TldD/E_C.
DR   InterPro; IPR045570; Metalloprtase-TldD/E_cen_dom.
DR   InterPro; IPR002510; Metalloprtase-TldD/E_N.
DR   InterPro; IPR047657; PmbA.
DR   InterPro; IPR035068; TldD/PmbA_N.
DR   InterPro; IPR036059; TldD/PmbA_sf.
DR   PANTHER; PTHR43421; METALLOPROTEASE PMBA; 1.
DR   PANTHER; PTHR43421:SF1; METALLOPROTEASE PMBA; 1.
DR   Pfam; PF01523; PmbA_TldD_1st; 1.
DR   Pfam; PF19290; PmbA_TldD_2nd; 1.
DR   Pfam; PF19289; PmbA_TldD_3rd; 1.
DR   SUPFAM; SSF111283; Putative modulator of DNA gyrase, PmbA/TldD; 1.
PE   3: Inferred from homology;
FT   DOMAIN          27..91
FT                   /note="Metalloprotease TldD/E N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01523"
FT   DOMAIN          121..224
FT                   /note="Metalloprotease TldD/E central"
FT                   /evidence="ECO:0000259|Pfam:PF19290"
FT   DOMAIN          231..453
FT                   /note="Metalloprotease TldD/E C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF19289"
SQ   SEQUENCE   455 AA;  48724 MW;  27EC933540B8407D CRC64;
     MTHTPLNVKE LRDQLHTLAT RDGIRRWDLG ASRGMNASVQ VDRGEAKQMK AAQRSSITVR
     VWNEQGLVGV TSTSDLSPGG LEKALHGAYQ ASSFGNTEDI PGFSPLATAP IPELDRPLKP
     SQSIQKLLST LKEVEGELLS KHPAIETVPY NGLTEGNSER IYLNSEGALR HMQRTQASLY
     LYARAEESGR KPRSGGAVRV ALGSADLDLA GCIKEAAERT ISHLNYKPID TGRYLVCFTP
     EAFLDLIGAF SSMLNARSIL DGVSLSSKES LGQQLAVPFF NLHDNGLHPD HVGAAAFDGE
     GTPTKRLCLI GNGTLENLLH SEATARQFGV SPTGHAGLGA KVSVGPDWFE VSSSQGLISP
     SPHLDHRSTQ EPFVLIESLS ALHAGVKASQ GAFSLPFDGW LVKDGERISV EAATIAGDIR
     EVLKGIVHLE PHEVVTHQGV SPHVWVDGLA ITGEA
//