ID G4QHD2_GLANF Unreviewed; 1016 AA.
AC G4QHD2;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(S) {ECO:0000313|EMBL:AEP29763.1};
GN OrderedLocusNames=GNIT_1647 {ECO:0000313|EMBL:AEP29763.1};
OS Glaciecola nitratireducens (strain JCM 12485 / KCTC 12276 / FR1064).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Alteromonadaceae; Glaciecola.
OX NCBI_TaxID=1085623 {ECO:0000313|EMBL:AEP29763.1, ECO:0000313|Proteomes:UP000009282};
RN [1] {ECO:0000313|EMBL:AEP29763.1, ECO:0000313|Proteomes:UP000009282}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 12485 / KCTC 12276 / FR1064
RC {ECO:0000313|Proteomes:UP000009282};
RX PubMed=22123761; DOI=10.1128/JB.06296-11;
RA Bian F., Qin Q.L., Xie B.B., Shu Y.L., Zhang X.Y., Yu Y., Chen B.,
RA Chen X.L., Zhou B.C., Zhang Y.Z.;
RT "Complete genome sequence of seawater bacterium Glaciecola nitratireducens
RT FR1064T.";
RL J. Bacteriol. 193:7006-7007(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ammonia transporter channel (TC 1.A.11.2)
CC family. {ECO:0000256|ARBA:ARBA00005887}.
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DR EMBL; CP003060; AEP29763.1; -; Genomic_DNA.
DR RefSeq; WP_014108637.1; NC_016041.1.
DR AlphaFoldDB; G4QHD2; -.
DR STRING; 1085623.GNIT_1647; -.
DR KEGG; gni:GNIT_1647; -.
DR eggNOG; COG0004; Bacteria.
DR eggNOG; COG5001; Bacteria.
DR HOGENOM; CLU_000445_33_6_6; -.
DR OrthoDB; 9816034at2; -.
DR Proteomes; UP000009282; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008519; F:ammonium transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 1.10.3430.10; Ammonium transporter AmtB like domains; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR029020; Ammonium/urea_transptr.
DR InterPro; IPR001905; Ammonium_transpt.
DR InterPro; IPR018047; Ammonium_transpt_CS.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR024041; NH4_transpt_AmtB-like_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00836; amt; 1.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00909; Ammonium_transp; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00989; PAS; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF111352; Ammonium transporter; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS01219; AMMONIUM_TRANSP; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50112; PAS; 1.
PE 3: Inferred from homology;
KW Ammonia transport {ECO:0000256|ARBA:ARBA00023177};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009282};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..23
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 44..64
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 84..106
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 113..134
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 154..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 188..211
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 226..249
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 256..276
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 282..299
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 306..328
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 343..365
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 455..526
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 617..750
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 759..1013
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 1016 AA; 112628 MW; 180CC8A563B2C827 CRC64;
MDYGWLLLSS MLVFLMQAGF LCLETGKIRS KNSINVAAKN ISDFIIAAII FWLFGFALMF
GDSFNGFIGT STLFFGANNS PYQISFFIFQ MMFCGTAATI LSGAVAERMS FRAYLYATIL
LTSIIYPISG HWAWASFYNE NNIGWLQALG FVDFAGSTVV HSVGGWVALA AIIIIGPRLG
RFDSAIPFPI GSNIPLSVLG TLLIWLGWFG FNGGSTLVFG DQVPGILLNT TLAAAWGGIS
AAAFHYYVYR YVDVTFIMNG VIAGLVAITA SCHAVSPQAS AIIGGIAGVI LVSGTLWINK
LKIDDALGVV PAHLFAGIWG TIAVAIFADL SLLDTGLSRP EQLFAQLVGI AAIGAYAFVI
GFVGLKVINK IHPLRVSAEY ELQGMNVSEH KASTELVDLL NNMHSQETRG NFSEPVPVEP
FTEVGQIANQ YNNVIQRVTD EIGKRDSAID RFRSSEKRKS AILDSSMDSI LSIDFKGNII
EFNHAAELTF GYLKQQVAGK NILSLFIPTE QQQKFVMSLE HKFAAADGLL INRRNSFRLQ
GHSGHLFPAE ITITSTNVND DLRNEYTWHV RDVTREVKLQ TKLKQLAYSD PLTGLYNRTF
LLQTLSRTLS YQIKSEGIVA VFFMDLDKFK KINDTLGHKA GDQLLNEVAH RLTQSTRNSD
TIARWGGDEF VVMIAGDVNI ALIHAKAREF LKVMREPMDL AGRQINIPVS IGIAVAIDED
ITAEQLIQHA DIAMYSAKQK GRDHFQFFHP DMAHKALKQF NFEQSIRQAL QESDQFFLNY
QPKIDAQRSI IGFEALVRWL HPEEGLIMPG EFIPLAEESD CIILLDKKVI HQAIEQLQVW
REQNLKLLPV SINISGKHLI SGNLVSFIQA ELERSGLDGS LIELEITEGV LLTDFERCIT
VMTELKTLNI SLSIDDFGTG YSSLNYLKRL PIDILKIDRS FVEECDTLKE DGQIVSTIIS
LAHNLELKTI AEGVETLEQF NFLLSKGCEA FQGYYFYRPL SSADICTLLK ALGNSH
//
