ID G4T2S5_META2 Unreviewed; 364 AA.
AC G4T2S5;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Efflux transporter, RND family, MFP subunit {ECO:0000313|EMBL:CCE22559.1};
GN OrderedLocusNames=MEALZ_0865 {ECO:0000313|EMBL:CCE22559.1};
OS Methylotuvimicrobium alcaliphilum (strain DSM 19304 / NCIMB 14124 / VKM
OS B-2133 / 20Z) (Methylomicrobium alcaliphilum).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Methylococcales;
OC Methylococcaceae; Methylotuvimicrobium.
OX NCBI_TaxID=1091494 {ECO:0000313|EMBL:CCE22559.1, ECO:0000313|Proteomes:UP000008315};
RN [1] {ECO:0000313|Proteomes:UP000008315}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19304 / NCIMB 14124 / VKM B-2133 / 20Z
RC {ECO:0000313|Proteomes:UP000008315};
RX PubMed=22207753; DOI=10.1128/JB.06392-11;
RA Vuilleumier S., Khmelenina V.N., Bringel F., Reshetnikov A.S., Lajus A.,
RA Mangenot S., Rouy Z., Op den Camp H.J., Jetten M.S., Dispirito A.A.,
RA Dunfield P., Klotz M.G., Semrau J.D., Stein L.Y., Barbe V., Medigue C.,
RA Trotsenko Y.A., Kalyuzhnaya M.G.;
RT "Genome sequence of the haloalkaliphilic methanotrophic bacterium
RT Methylomicrobium alcaliphilum 20Z.";
RL J. Bacteriol. 194:551-552(2012).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; FO082060; CCE22559.1; -; Genomic_DNA.
DR AlphaFoldDB; G4T2S5; -.
DR STRING; 1091494.MEALZ_0865; -.
DR KEGG; mah:MEALZ_0865; -.
DR PATRIC; fig|271065.3.peg.881; -.
DR HOGENOM; CLU_018816_1_2_6; -.
DR Proteomes; UP000008315; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469:SF11; BLL4320 PROTEIN; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008315}.
FT DOMAIN 69..267
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
SQ SEQUENCE 364 AA; 39894 MW; 5D3F11965215020B CRC64;
MLKRFLILIL FSVLIFGGIF GLKFYQLHQE AGQFQPPPPA VVAATEVTQE IWPSALSAVG
SLTAIAGVDV SNEVAGKVEA IHFDSGQSVK KGQLLLELDA STDRAELQGL QAEMRLAKVR
FERSEKLIGK NFISQSDYDQ NHALLDETAA AVHAKRTLID RKRIRAPFTG ELGIRLVNLG
QYLTEGSAIV SLQQLDPIYL DFTVPERYLN RLVKGRQVIA TVQAYPGREF NGEISAVSPL
IDQGTRSVQV RAKLSNSEKL LHPGIFAQIG ILSDQELNVL TLPDTAITYN PYGNSVFVIE
TNEQGLIVQS RQVETGQTRA GRVEIINGLK LGERVVSAGQ VKLRNGMPVT LDDKPAPGER
EISQ
//
