ID   G4TBB6_SERID            Unreviewed;       658 AA.
AC   G4TBB6;
DT   14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2011, sequence version 1.
DT   27-MAR-2024, entry version 49.
DE   SubName: Full=Related to cullin 4A {ECO:0000313|EMBL:CCA68590.1};
GN   ORFNames=PIIN_02455 {ECO:0000313|EMBL:CCA68590.1};
OS   Serendipita indica (strain DSM 11827) (Root endophyte fungus)
OS   (Piriformospora indica).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Sebacinales; Serendipitaceae; Serendipita.
OX   NCBI_TaxID=1109443 {ECO:0000313|EMBL:CCA68590.1, ECO:0000313|Proteomes:UP000007148};
RN   [1] {ECO:0000313|EMBL:CCA68590.1, ECO:0000313|Proteomes:UP000007148}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 11827 {ECO:0000313|EMBL:CCA68590.1,
RC   ECO:0000313|Proteomes:UP000007148};
RX   PubMed=22022265; DOI=10.1371/journal.ppat.1002290;
RA   Zuccaro A., Lahrmann U., Guldener U., Langen G., Pfiffi S., Biedenkopf D.,
RA   Wong P., Samans B., Grimm C., Basiewicz M., Murat C., Martin F.,
RA   Kogel K.H.;
RT   "Endophytic Life Strategies Decoded by Genome and Transcriptome Analyses of
RT   the Mutualistic Root Symbiont Piriformospora indica.";
RL   PLoS Pathog. 7:e1002290-e1002290(2011).
CC   -!- SIMILARITY: Belongs to the cullin family.
CC       {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC       ECO:0000256|RuleBase:RU003829}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCA68590.1}.
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DR   EMBL; CAFZ01000036; CCA68590.1; -; Genomic_DNA.
DR   AlphaFoldDB; G4TBB6; -.
DR   STRING; 1109443.G4TBB6; -.
DR   eggNOG; KOG2167; Eukaryota.
DR   HOGENOM; CLU_004747_7_3_1; -.
DR   InParanoid; G4TBB6; -.
DR   OMA; WCVENEY; -.
DR   OrthoDB; 5474206at2759; -.
DR   Proteomes; UP000007148; Unassembled WGS sequence.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 1.20.1310.10; Cullin Repeats; 3.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR045093; Cullin.
DR   InterPro; IPR016158; Cullin_homology.
DR   InterPro; IPR036317; Cullin_homology_sf.
DR   InterPro; IPR001373; Cullin_N.
DR   InterPro; IPR019559; Cullin_neddylation_domain.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11932; CULLIN; 1.
DR   PANTHER; PTHR11932:SF126; CULLIN 4, ISOFORM A; 1.
DR   Pfam; PF00888; Cullin; 1.
DR   Pfam; PF10557; Cullin_Nedd8; 1.
DR   SMART; SM00182; CULLIN; 1.
DR   SMART; SM00884; Cullin_Nedd8; 1.
DR   SUPFAM; SSF75632; Cullin homology domain; 1.
DR   SUPFAM; SSF74788; Cullin repeat-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50069; CULLIN_2; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000007148}.
FT   DOMAIN          287..521
FT                   /note="Cullin family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50069"
SQ   SEQUENCE   658 AA;  75736 MW;  3E37D16887DC8F55 CRC64;
     MTKLNDRWSW WLRRIRVLRS ALVYLDVAYL ATNEDKLTIQ DAAFHRFEDT VVASTTVTLK
     LEAALKRWSE QRRAGENTED YDDQLRLVVD CMSTLGCYDD QVHQPYLRFT SDHYTKKSQM
     APETNAKDYL LMCIQDISDE ERRGADILRE ETRRDASVTA LSGLAMEHMD YLAKDGLAEI
     ITSRNKTLFH QLYNLIGRLT SVSTTWKTSP SDALLAHYRN DVFERVKGTI LDTANESSMV
     ENLLELKEFL DECLSADYID DAQQNDRKFT HATSEAFERG FSTRKIKPAE LIAKHVDSLM
     RRGQKAASDQ EFFAQLKRDA VYLPTIPDKD VFRAFYTRAL AKRLLLGRSA SDDFEKQVLA
     ELSKSYDAAF SDMTQMFNDL AISKDLMETY RNTKDQEPAR PDPSLTVMVL QHSVWPVIRK
     VSKLDAPVEL RLPSQMEHAL NDFIAFYKTQ HSNRKLTWAH YLGTATLVAR FPSGKKELSV
     SLYQAAVLLL FSERDDWSTE EIHGRLGLAL PDLTPTLQSL ALGRKLVLRR TQPRQGKDVR
     MDDRFSFNED FTDTKVKLHI NTIQQNDTME ETQQAVKVID QYREASLDAA IVRIMKAAKT
     MKHQQLVNET IDAVSKHFRP EVKAIKERID SLIEREFLQR NEDTGGSNKL RDTYSYLA
//