ID   G4TIN1_SERID            Unreviewed;       451 AA.
AC   G4TIN1;
DT   14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2011, sequence version 1.
DT   27-MAR-2024, entry version 43.
DE   SubName: Full=Related to SPT14-N-acetylglucosaminyltransferase {ECO:0000313|EMBL:CCA71174.1};
GN   ORFNames=PIIN_05110 {ECO:0000313|EMBL:CCA71174.1};
OS   Serendipita indica (strain DSM 11827) (Root endophyte fungus)
OS   (Piriformospora indica).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Sebacinales; Serendipitaceae; Serendipita.
OX   NCBI_TaxID=1109443 {ECO:0000313|EMBL:CCA71174.1, ECO:0000313|Proteomes:UP000007148};
RN   [1] {ECO:0000313|EMBL:CCA71174.1, ECO:0000313|Proteomes:UP000007148}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 11827 {ECO:0000313|EMBL:CCA71174.1,
RC   ECO:0000313|Proteomes:UP000007148};
RX   PubMed=22022265; DOI=10.1371/journal.ppat.1002290;
RA   Zuccaro A., Lahrmann U., Guldener U., Langen G., Pfiffi S., Biedenkopf D.,
RA   Wong P., Samans B., Grimm C., Basiewicz M., Murat C., Martin F.,
RA   Kogel K.H.;
RT   "Endophytic Life Strategies Decoded by Genome and Transcriptome Analyses of
RT   the Mutualistic Root Symbiont Piriformospora indica.";
RL   PLoS Pathog. 7:e1002290-e1002290(2011).
CC   -!- FUNCTION: Catalytic subunit in the complex catalyzing the transfer of
CC       N-acetylglucosamine from UDP-N-acetylglucosamine to
CC       phosphatidylinositol, the first step of GPI biosynthesis.
CC       {ECO:0000256|ARBA:ARBA00003265}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCA71174.1}.
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DR   EMBL; CAFZ01000109; CCA71174.1; -; Genomic_DNA.
DR   AlphaFoldDB; G4TIN1; -.
DR   STRING; 1109443.G4TIN1; -.
DR   eggNOG; KOG1111; Eukaryota.
DR   HOGENOM; CLU_009583_19_0_1; -.
DR   InParanoid; G4TIN1; -.
DR   OMA; QCVLPTM; -.
DR   OrthoDB; 24420at2759; -.
DR   Proteomes; UP000007148; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0017176; F:phosphatidylinositol N-acetylglucosaminyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006506; P:GPI anchor biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR   InterPro; IPR001296; Glyco_trans_1.
DR   InterPro; IPR013234; PIGA_GPI_anchor_biosynthesis.
DR   PANTHER; PTHR45871; N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROTEIN; 1.
DR   PANTHER; PTHR45871:SF1; PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT A; 1.
DR   Pfam; PF00534; Glycos_transf_1; 1.
DR   Pfam; PF08288; PIGA; 1.
DR   SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE   4: Predicted;
KW   Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676,
KW   ECO:0000313|EMBL:CCA71174.1}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007148};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:CCA71174.1};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        408..427
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          36..111
FT                   /note="PIGA GPI anchor biosynthesis"
FT                   /evidence="ECO:0000259|Pfam:PF08288"
FT   DOMAIN          204..350
FT                   /note="Glycosyl transferase family 1"
FT                   /evidence="ECO:0000259|Pfam:PF00534"
SQ   SEQUENCE   451 AA;  51003 MW;  66BF999DC0FE6B27 CRC64;
     MVCDFFHPNI GGVENHIYIL SVNLLRRGHK VVAVTHSYPD SRVGIRWLAP GIKVYHVPLR
     VLVSNATLPN YLTFLPWLRD IVLRERITII HGHASLSSFA QEAILHSHLF GSGFESMFGW
     WRRNGEQEES REIRTVFTDH SLFALDDATG ILTNKLLAAA LNNVDAVICV SHTARENTVL
     RAQIDPRTAY VIPSAVIAEQ FKPPPKPLST DTITIVVISR LAYRKGVDLL VASAPRICAL
     FPQVQFLVGG SGPKLINLLQ MREAHRLQDR ITLLGAVDHH DVRNVLVQGH IYLNTSLTES
     FGIGLLEAAC TGCFIVSTRV GGVPEVLPKD MIEFAMPNED DVVRALRKAI AIVTAGKHDP
     YRAHERAKSM YTWEDVTKRT ETVYADIVKK RPTDLWTRMH RTLRLGPFAG LIYFIILLVE
     CLFFLFLEWV CPRDQIHYVE EDWTMESFKQ V
//