ID   G4TTS1_SERID            Unreviewed;       720 AA.
AC   G4TTS1;
DT   14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2011, sequence version 1.
DT   24-JAN-2024, entry version 45.
DE   RecName: Full=Anaphase-promoting complex subunit 2 {ECO:0000256|ARBA:ARBA00016068};
GN   ORFNames=PIIN_08674 {ECO:0000313|EMBL:CCA74714.1};
OS   Serendipita indica (strain DSM 11827) (Root endophyte fungus)
OS   (Piriformospora indica).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Sebacinales; Serendipitaceae; Serendipita.
OX   NCBI_TaxID=1109443 {ECO:0000313|EMBL:CCA74714.1, ECO:0000313|Proteomes:UP000007148};
RN   [1] {ECO:0000313|EMBL:CCA74714.1, ECO:0000313|Proteomes:UP000007148}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 11827 {ECO:0000313|EMBL:CCA74714.1,
RC   ECO:0000313|Proteomes:UP000007148};
RX   PubMed=22022265; DOI=10.1371/journal.ppat.1002290;
RA   Zuccaro A., Lahrmann U., Guldener U., Langen G., Pfiffi S., Biedenkopf D.,
RA   Wong P., Samans B., Grimm C., Basiewicz M., Murat C., Martin F.,
RA   Kogel K.H.;
RT   "Endophytic Life Strategies Decoded by Genome and Transcriptome Analyses of
RT   the Mutualistic Root Symbiont Piriformospora indica.";
RL   PLoS Pathog. 7:e1002290-e1002290(2011).
CC   -!- SIMILARITY: Belongs to the cullin family. {ECO:0000256|PROSITE-
CC       ProRule:PRU00330, ECO:0000256|RuleBase:RU003829}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCA74714.1}.
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DR   EMBL; CAFZ01000346; CCA74714.1; -; Genomic_DNA.
DR   AlphaFoldDB; G4TTS1; -.
DR   STRING; 1109443.G4TTS1; -.
DR   eggNOG; KOG2165; Eukaryota.
DR   HOGENOM; CLU_007149_4_2_1; -.
DR   InParanoid; G4TTS1; -.
DR   OMA; FMYETFA; -.
DR   OrthoDB; 2786196at2759; -.
DR   Proteomes; UP000007148; Unassembled WGS sequence.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 1.20.1310.10; Cullin Repeats; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR044554; APC2-like.
DR   InterPro; IPR014786; APC2_C.
DR   InterPro; IPR016158; Cullin_homology.
DR   InterPro; IPR036317; Cullin_homology_sf.
DR   InterPro; IPR001373; Cullin_N.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR45957; ANAPHASE-PROMOTING COMPLEX SUBUNIT 2; 1.
DR   PANTHER; PTHR45957:SF1; ANAPHASE-PROMOTING COMPLEX SUBUNIT 2; 1.
DR   Pfam; PF08672; ANAPC2; 1.
DR   Pfam; PF00888; Cullin; 1.
DR   SMART; SM00182; CULLIN; 1.
DR   SUPFAM; SSF75632; Cullin homology domain; 1.
DR   PROSITE; PS50069; CULLIN_2; 1.
PE   3: Inferred from homology;
KW   Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW   Cell division {ECO:0000256|ARBA:ARBA00022618};
KW   Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007148};
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT   DOMAIN          424..611
FT                   /note="Cullin family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50069"
SQ   SEQUENCE   720 AA;  82466 MW;  D620AF35E4188AC1 CRC64;
     MATEAELRAI WEEKLQRISG GKKDVDREKK LANFSQIWDA VLPRIQPKSV PIEKEGSQEA
     AIFAKLADPS VARTAYTIAI DTMRQKQDLL RHDLEKAIDT CEETGDAAAF AEIFDTLARW
     RTTWYEPFKN NQKIISSQEF TTSFNLILLH ALPPTFPGAL TEFLEATLVS PDTAFDHTFS
     LLTSLGLTRN FETLICRVAY RAIERRVEEV CPGEWESPCL RDILDWVKNT LVPWSTRIFS
     FDNDPSHLAG HSGDKNIGLK FEFHVYKTVF DLRVSELFDI ISDVEGEAQV LKDLKECMGR
     VSGRTEIVRS IRQQIAKRLL HPGADTKDII DFYISMIRCL RVIDRQGVLL FRVADPIRAY
     LRDRPDTISY IVSQLVDEKS ELAQEAQAPI VSEMEHEDYS DPKWMPEPPD AGPKFRTMRP
     SDLISTLVSI YDSHELFIKE LQTLFSTLFL QSREDSFDAE KRQLEILKLR FGDTALQSID
     VMLADMQSAV RVHKQIQETE ESVLKPAIIS RWFWPEAPEP DTFKMPGQLQ EEYNKRYQKV
     KPDKRLHWVQ SMGTLKLTIE LSDRQVEVNA TPLEAAVIEL FSSKSSWLQE ELSKQLGVKE
     KDVLGALISW NEEGVLEFNS YTKRWILVEE GDASRVQPAP APTIERFPEL QPSAMSSREQ
     QHWQHIKGAL SNFGTCSTER IHKLMRYTAD PITLDQLNAL MGRLQADGLV EGMDSVWRLI
//