ID G4VRQ7_SCHMA Unreviewed; 616 AA.
AC G4VRQ7;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Kelch-like ech-associated protein {ECO:0000313|WBParaSite:Smp_085380.1};
OS Schistosoma mansoni (Blood fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=6183 {ECO:0000313|Proteomes:UP000008854, ECO:0000313|WBParaSite:Smp_085380.1};
RN [1] {ECO:0000313|Proteomes:UP000008854}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Puerto Rican {ECO:0000313|Proteomes:UP000008854};
RX PubMed=22253936; DOI=10.1371/journal.pntd.0001455;
RA Protasio A.V., Tsai I.J., Babbage A., Nichol S., Hunt M., Aslett M.A.,
RA De Silva N., Velarde G.S., Anderson T.J., Clark R.C., Davidson C.,
RA Dillon G.P., Holroyd N.E., LoVerde P.T., Lloyd C., McQuillan J.,
RA Oliveira G., Otto T.D., Parker-Manuel S.J., Quail M.A., Wilson R.A.,
RA Zerlotini A., Dunne D.W., Berriman M.;
RT "A systematically improved high quality genome and transcriptome of the
RT human blood fluke Schistosoma mansoni.";
RL PLoS Negl. Trop. Dis. 6:E1455-E1455(2012).
RN [2] {ECO:0000313|WBParaSite:Smp_085380.1}
RP IDENTIFICATION.
RC STRAIN=Puerto Rican {ECO:0000313|WBParaSite:Smp_085380.1};
RG WormBaseParasite;
RL Submitted (DEC-2018) to UniProtKB.
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DR RefSeq; XP_018655331.1; XM_018789938.1.
DR AlphaFoldDB; G4VRQ7; -.
DR STRING; 6183.G4VRQ7; -.
DR EnsemblMetazoa; Smp_085380.1; Smp_085380.1; Smp_085380.
DR GeneID; 8347064; -.
DR KEGG; smm:Smp_085380; -.
DR WBParaSite; Smp_085380.1; Smp_085380.1; Smp_085380.
DR CTD; 8347064; -.
DR eggNOG; KOG4441; Eukaryota.
DR HOGENOM; CLU_004253_14_2_1; -.
DR InParanoid; G4VRQ7; -.
DR OMA; CYHPEND; -.
DR OrthoDB; 5472491at2759; -.
DR PhylomeDB; G4VRQ7; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000008854; Unassembled WGS sequence.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR24412:SF498; BTB DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24412; KELCH PROTEIN; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 6.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 6.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000008854};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 85..152
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
SQ SEQUENCE 616 AA; 69342 MW; 47DD8B69E9A9C825 CRC64;
MIMKENVEDF PMDELSVSST NRDISSSFPD LANSELYIPH PTYILPTCSS NESNDNLICM
NFELNHYLKE AMNTMYELFQ SQKLTDVTLC VNSESIQCHR IVLAGASPYF RAMFTGEMRE
ALLHEIKLHY ISATALKKLI DFAYTGRIQI SERNVCELLI AASMIQMSHV VQACCSFLKQ
QLHPSNAIGI QEFAQSNNCS ELSFAAQKFI DQNFGEIVKH DEFLGLHPNQ LLTLIKRDEL
NVRTEAEVYN AVIRWVNHNR NSRSSTLLEA LSAVRCYTLP PTFIQGQIKN CSLLAGFTPA
KSHLQNILDD LIKHRHISIN KRTAGSMEIL YSAGGYLRYS LSAFECYNPL TDKWRRLPDI
PSPRSGLSAC SVRGCVYLVG GRNNNEQGNI DAPHMDCYDP RKNCWTTCAP MSVPRNRVAV
GVVDDMIYAV GGSTNTMHHK SSEKYDPDMD QWIPIASMNS RRIGLGVAVL NRLLYAVGGF
DGEKRLNTVE RYDPEKDHWE ELACLNRARS GAGVVALGEY IYAIGGYDSC SQLNTMERYD
PKRNCWEYCA SMLHPRSALS ASVWGNEIWV FGGYDGSEFL ASVEVYNPIK DQWTERTFMD
CGKSGHAVVV SRGPSF
//
