ID G4YM36_PHYSP Unreviewed; 642 AA.
AC G4YM36;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 24-JAN-2024, entry version 50.
DE RecName: Full=FYVE-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PHYSODRAFT_293391 {ECO:0000313|EMBL:EGZ27566.1};
OS Phytophthora sojae (strain P6497) (Soybean stem and root rot agent)
OS (Phytophthora megasperma f. sp. glycines).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=1094619 {ECO:0000313|EMBL:EGZ27566.1, ECO:0000313|Proteomes:UP000002640};
RN [1] {ECO:0000313|EMBL:EGZ27566.1, ECO:0000313|Proteomes:UP000002640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P6497 {ECO:0000313|EMBL:EGZ27566.1,
RC ECO:0000313|Proteomes:UP000002640};
RX PubMed=16946064; DOI=10.1126/science.1128796;
RA Tyler B.M., Tripathy S., Zhang X., Dehal P., Jiang R.H., Aerts A.,
RA Arredondo F.D., Baxter L., Bensasson D., Beynon J.L., Chapman J.,
RA Damasceno C.M., Dorrance A.E., Dou D., Dickerman A.W., Dubchak I.L.,
RA Garbelotto M., Gijzen M., Gordon S.G., Govers F., Grunwald N.J., Huang W.,
RA Ivors K.L., Jones R.W., Kamoun S., Krampis K., Lamour K.H., Lee M.K.,
RA McDonald W.H., Medina M., Meijer H.J., Nordberg E.K., Maclean D.J.,
RA Ospina-Giraldo M.D., Morris P.F., Phuntumart V., Putnam N.H., Rash S.,
RA Rose J.K., Sakihama Y., Salamov A.A., Savidor A., Scheuring C.F.,
RA Smith B.M., Sobral B.W., Terry A., Torto-Alalibo T.A., Win J., Xu Z.,
RA Zhang H., Grigoriev I.V., Rokhsar D.S., Boore J.L.;
RT "Phytophthora genome sequences uncover evolutionary origins and mechanisms
RT of pathogenesis.";
RL Science 313:1261-1266(2006).
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DR EMBL; JH159151; EGZ27566.1; -; Genomic_DNA.
DR RefSeq; XP_009514841.1; XM_009516546.1.
DR AlphaFoldDB; G4YM36; -.
DR STRING; 1094619.G4YM36; -.
DR EnsemblProtists; EGZ27566; EGZ27566; PHYSODRAFT_293391.
DR GeneID; 20640977; -.
DR KEGG; psoj:PHYSODRAFT_293391; -.
DR InParanoid; G4YM36; -.
DR OMA; IEINECP; -.
DR Proteomes; UP000002640; Unassembled WGS sequence.
DR GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd00065; FYVE_like_SF; 1.
DR Gene3D; 3.30.530.20; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR023393; START-like_dom_sf.
DR InterPro; IPR002913; START_lipid-bd_dom.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13510; FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED; 1.
DR PANTHER; PTHR13510:SF44; RABENOSYN-5; 1.
DR Pfam; PF01363; FYVE; 1.
DR Pfam; PF01852; START; 1.
DR SMART; SM00064; FYVE; 1.
DR SUPFAM; SSF55961; Bet v1-like; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS50848; START; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000002640};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 19..245
FT /note="START"
FT /evidence="ECO:0000259|PROSITE:PS50848"
FT DOMAIN 272..332
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT REGION 406..460
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 504..642
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 420..434
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 559..573
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 582..597
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 642 AA; 69990 MW; 41D73D0EC902BB2F CRC64;
MSTSLPLPKG FFNTNVHVSE DMRRQYVEFA EGSIRKVFAL SDCHKNSWIP MREKKGVAIY
RNFGQMRGPN AYKSNIAEVG CKGELNASLE QVGRAYAAHD DALFRRLMKK LNPAVMDAAV
LSTIVPRTPL TPYRYIGIKW YAVKTPTPIV SHRDYCCLEV QDKIVDSFGN EMYIRVLNSI
EVNECPSLEN SHGLVRAKIL AGYMYRTDRA EPNVVRVHHV ARLDPGGYFP SQWAFKTAES
QLVNSIVQIR RIIDKQQMNA CTFVDKRQWV PNHERLHCAV CSRTFGTFRP RHHCRSCGEV
ICGKCSVFKS VEVPGTTLKN VRICSVCNMG VQKAGGHDDG NMSDISTSSV TSSSTIAHNE
MNLMDLYMGN GGGPRTPSAF SDASAHSNLS IRSTTSTRSV YDARGHAHSH ARGPRTPGGA
FFNESNTPRS YIANNLTPRG FGFGSGPPTP GSAATTPSGG ARPSISAASV VAAAAITAQR
LSNYKQNPVD LGYLRDSVNE TTATAAHAPE AAAHERPEDP TTPWPPVKIQ RLETGETADV
DMEADEEDDM ETKPAAPLAS DTQEAQQQRR PLGLQLPTVE RISESPFEQS SASTVFRASL
DKDEPASSSN AGAGGGGFRP FFNGILSRVR GDSGEKSSQR AA
//
