ID G4Z717_PHYSP Unreviewed; 1063 AA.
AC G4Z717;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=NFACT RNA-binding domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PHYSODRAFT_557667 {ECO:0000313|EMBL:EGZ21769.1};
OS Phytophthora sojae (strain P6497) (Soybean stem and root rot agent)
OS (Phytophthora megasperma f. sp. glycines).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=1094619 {ECO:0000313|EMBL:EGZ21769.1, ECO:0000313|Proteomes:UP000002640};
RN [1] {ECO:0000313|EMBL:EGZ21769.1, ECO:0000313|Proteomes:UP000002640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P6497 {ECO:0000313|EMBL:EGZ21769.1,
RC ECO:0000313|Proteomes:UP000002640};
RX PubMed=16946064; DOI=10.1126/science.1128796;
RA Tyler B.M., Tripathy S., Zhang X., Dehal P., Jiang R.H., Aerts A.,
RA Arredondo F.D., Baxter L., Bensasson D., Beynon J.L., Chapman J.,
RA Damasceno C.M., Dorrance A.E., Dou D., Dickerman A.W., Dubchak I.L.,
RA Garbelotto M., Gijzen M., Gordon S.G., Govers F., Grunwald N.J., Huang W.,
RA Ivors K.L., Jones R.W., Kamoun S., Krampis K., Lamour K.H., Lee M.K.,
RA McDonald W.H., Medina M., Meijer H.J., Nordberg E.K., Maclean D.J.,
RA Ospina-Giraldo M.D., Morris P.F., Phuntumart V., Putnam N.H., Rash S.,
RA Rose J.K., Sakihama Y., Salamov A.A., Savidor A., Scheuring C.F.,
RA Smith B.M., Sobral B.W., Terry A., Torto-Alalibo T.A., Win J., Xu Z.,
RA Zhang H., Grigoriev I.V., Rokhsar D.S., Boore J.L.;
RT "Phytophthora genome sequences uncover evolutionary origins and mechanisms
RT of pathogenesis.";
RL Science 313:1261-1266(2006).
CC -!- SIMILARITY: Belongs to the NEMF family.
CC {ECO:0000256|ARBA:ARBA00008318}.
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DR EMBL; JH159153; EGZ21769.1; -; Genomic_DNA.
DR RefSeq; XP_009524486.1; XM_009526191.1.
DR AlphaFoldDB; G4Z717; -.
DR STRING; 1094619.G4Z717; -.
DR EnsemblProtists; EGZ21769; EGZ21769; PHYSODRAFT_557667.
DR GeneID; 20663267; -.
DR KEGG; psoj:PHYSODRAFT_557667; -.
DR InParanoid; G4Z717; -.
DR OMA; MFLEFFA; -.
DR Proteomes; UP000002640; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0072344; P:rescue of stalled ribosome; IEA:UniProt.
DR Gene3D; 2.30.310.10; ibrinogen binding protein from staphylococcus aureus domain; 1.
DR InterPro; IPR021846; NFACT-C.
DR InterPro; IPR008532; NFACT_RNA-bd.
DR PANTHER; PTHR15239; NUCLEAR EXPORT MEDIATOR FACTOR NEMF; 1.
DR PANTHER; PTHR15239:SF6; RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT NEMF; 1.
DR Pfam; PF11923; NFACT-C; 1.
DR Pfam; PF05670; NFACT-R_1; 1.
DR Pfam; PF05833; NFACT_N; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000002640}.
FT DOMAIN 579..698
FT /note="NFACT RNA-binding"
FT /evidence="ECO:0000259|Pfam:PF05670"
FT DOMAIN 914..1034
FT /note="NFACT protein C-terminal"
FT /evidence="ECO:0000259|Pfam:PF11923"
FT REGION 286..318
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 726..919
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 977..1006
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1035..1063
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 755..812
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 831..852
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 853..879
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 881..910
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1063 AA; 118848 MW; 52C85B81AA7831D7 CRC64;
MKKTRMSIDD IRAMVGSIRA NVQNMRVTNI YDVQGQGESG AAKTYILKLH QPPFPKVFLL
LESGVRFHTS KYARDAKAGS ALPSQFTMKL RKHLRGKRLS GLRQLEGDRV VDFTFGQDAL
QCHLILELYA SGNIVLTDGD YRILSLLRTH RFDENVKMAV KQVYPVQLLG DQEKQRAIQT
PAQLAAFVDK WFVEQEAKAA VALPGKTQKK KKAQTIKQLL LVKESTFGGL GPVIIEHCLV
RAGISPTLKL KNAAEFSALG DDKLAALLAE IQEGWKLLER LQDEQTSVNG PVPVQNDDTV
DAGDSDEEEA APVAKAPSSA SSQKCGFIIL KDSADENAPE QFEEFTPFLY AQHQQAHKKV
KSFDTFDEAV DEYFSRFEAD TAEVAKQSAQ LAAENKLAKL KKNQQQQLAQ LREVQEQSFQ
HAQLIEANQQ DVENVLLVIR SALASGMDWR GLEELVRYEQ KNGNPVASLI HKLDLEHNRV
AILLCDEEDD DEGEDGGDGT GEEDKQAHVI WIDLSLSALA NAREIYTKKK KAGEKVKKAT
EATDKAIALA EKNTKKTLEK QQTKRNVIYQ RRKTLWFEKF HWFLTNEKYL VVAGKDAHQN
ELLVKRYLRK GDVYVHADLH GAATCIVRNH ATVKDKKTQE LPPIPVATLE QAGCMSVCRS
NAWTSQVIAG AYWVHADQVS KTAPAGEYLT TGSFMIRGKK NYIQPSRLEM GLAVLFRIDE
SSISNHARQG EGRTQRAAED DHEEEQDEED ADQKEETPAQ QPQREGKKRL SAKERRDLKK
SKLPSRDDSI DEQHPAQQKR AKGKDKDKGP ASAPQQKKSV RGKKGKMKKM KKKYADQDEE
DRRLRMEALG HAVEEDQEEE EEPSKDGDDS AEQSGDENEE AADSTPSKKE ASEEYIRHQR
EKKEKYLDEQ EDEAEGADFF DAFTGEPLAD DIVLFAMPMC APYASLIKFK YKVKLTPGSQ
KKGKAAKQAM EHFFASNFKD EKDANKSAPY RPGGAEAEDE AQPDVNPIVV QRELMRCIPE
NELVNCMVGP VKISAPGLHG PNAGGKKGGG KRPSGKPKKK GKK
//
