ID G4ZT93_PHYSP Unreviewed; 1551 AA.
AC G4ZT93;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=Carrier domain-containing protein {ECO:0000259|PROSITE:PS50075};
GN ORFNames=PHYSODRAFT_514675 {ECO:0000313|EMBL:EGZ13125.1};
OS Phytophthora sojae (strain P6497) (Soybean stem and root rot agent)
OS (Phytophthora megasperma f. sp. glycines).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=1094619 {ECO:0000313|EMBL:EGZ13125.1, ECO:0000313|Proteomes:UP000002640};
RN [1] {ECO:0000313|EMBL:EGZ13125.1, ECO:0000313|Proteomes:UP000002640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P6497 {ECO:0000313|EMBL:EGZ13125.1,
RC ECO:0000313|Proteomes:UP000002640};
RX PubMed=16946064; DOI=10.1126/science.1128796;
RA Tyler B.M., Tripathy S., Zhang X., Dehal P., Jiang R.H., Aerts A.,
RA Arredondo F.D., Baxter L., Bensasson D., Beynon J.L., Chapman J.,
RA Damasceno C.M., Dorrance A.E., Dou D., Dickerman A.W., Dubchak I.L.,
RA Garbelotto M., Gijzen M., Gordon S.G., Govers F., Grunwald N.J., Huang W.,
RA Ivors K.L., Jones R.W., Kamoun S., Krampis K., Lamour K.H., Lee M.K.,
RA McDonald W.H., Medina M., Meijer H.J., Nordberg E.K., Maclean D.J.,
RA Ospina-Giraldo M.D., Morris P.F., Phuntumart V., Putnam N.H., Rash S.,
RA Rose J.K., Sakihama Y., Salamov A.A., Savidor A., Scheuring C.F.,
RA Smith B.M., Sobral B.W., Terry A., Torto-Alalibo T.A., Win J., Xu Z.,
RA Zhang H., Grigoriev I.V., Rokhsar D.S., Boore J.L.;
RT "Phytophthora genome sequences uncover evolutionary origins and mechanisms
RT of pathogenesis.";
RL Science 313:1261-1266(2006).
CC -!- SIMILARITY: Belongs to the NRP synthetase family.
CC {ECO:0000256|ARBA:ARBA00029454}.
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DR EMBL; JH159156; EGZ13125.1; -; Genomic_DNA.
DR RefSeq; XP_009530554.1; XM_009532259.1.
DR STRING; 1094619.G4ZT93; -.
DR EnsemblProtists; EGZ13125; EGZ13125; PHYSODRAFT_514675.
DR GeneID; 20659583; -.
DR KEGG; psoj:PHYSODRAFT_514675; -.
DR InParanoid; G4ZT93; -.
DR OMA; WEWHISA; -.
DR Proteomes; UP000002640; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0043604; P:amide biosynthetic process; IEA:UniProt.
DR GO; GO:0019752; P:carboxylic acid metabolic process; IEA:UniProt.
DR GO; GO:1901362; P:organic cyclic compound biosynthetic process; IEA:UniProt.
DR GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR CDD; cd05930; A_NRPS; 1.
DR CDD; cd19531; LCL_NRPS-like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 1.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR InterPro; IPR001031; Thioesterase.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF00668; Condensation; 1.
DR Pfam; PF00550; PP-binding; 1.
DR Pfam; PF00975; Thioesterase; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR PROSITE; PS00455; AMP_BINDING; 1.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 3: Inferred from homology;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000002640}.
FT DOMAIN 1225..1313
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1551 AA; 172765 MW; 35DA0628A37FA6F6 CRC64;
MRSAEEEEAD AARASGTHDN TNENAVDVAA LTCALDAGQV DVAVHWLQLL LLENGDRHQQ
PTKRRKALNR SRIRRLKTLQ NAVVQMLSDH DTDREEDTLT LRPGLAKATC ELSYSQLQMF
ALQRMQPSST AYNVVRALQF CDVPLDLTAL ESACHALMAK HEALRTCFDA DMNAGGQPRQ
IVHPLTYFQG KLGVFGVIQS ELLASRCNED SSRDGELAAL VAKVVDEPFD LAHQAPIRVY
ALVSPDQSPT SQWVLAVVLH HIVTDAASSQ IFWNDFHELH NRFRHSDDAM VSKTEFIQQL
ETQASSGSRV TYQDFAVWQR FRMRSGIMAP ALQYWMQQLT EGGAPPLLEL PFDSEAAISS
ASDEPKAPGS TTTEGDVVVF RSTPALQKAF SALCHAQGAS MFMGLLTVFY LLIERLSGQQ
DFVIGAPSSG RVRDELQDVM GYFVNTLPLR LGVKCSEVAD FTGFLASVRE VVLGAYNHME
IPFHKVLEHL RATAQSNRDV DGDAERRWQH PLFQIMFSWE NSDDDINADS SNANKHMELS
LPHHSAKFDL MLSMRYRQLK GGAAGDRVLE GSMEYPTARF TRGTVERFTG YYLTLLEQVT
NAPTAVVRSP TICMLSEAER RQLVSKWGMP KPPSSSYDKP SSFLDECLFF QVQKTQHSPA
LHFEGTEWTY RDLWEQSGRV TRALCMLDLP GCAAELHIGL LLDRGLQNIA AMVGTLRLKG
VFVPLDPEFP RERLRYMARD SGLQVIITQQ KHYEVARYLS ASVTNGSEDA DDLSPCVLCY
EDVDALTSLY GHSRDDIRSQ SRDSRDPHKA AAYILYTSGS TGNPKGVVVP HAALMTTLWW
TVRTYEVTSD DVFLQSTSTT LDGSLSQLFS PLLVGGSVRI TRPKGLHELH YMRNVLLEAP
HITFCVFVPS YFALIVDFLS DKGDSFPTSV KHVVLAGEAF PIELARQFYR KYQYSTACLV
NEYGPTEASI TSTAFQLPRE LAMQSTSSII EGLQSVPIGK PIDDHPVIVL DAQRRLVPVN
VPGELYIGGV GVARGYWHRP DLTVEAFIAH EDLHEIASIV PKRGRRWYKT GDLVKWLPSG
DLVFLGRTDA QVKHHGMRIE LQEVRNVLLR YSSIKTAEVL SISQPKSPGR KQRQTSSSSL
VAFVMLVDCV NDGSTGEEYI DKLRVYLRDR LPVHMVPQSI RVVSSWPRTP NGKIDLRALA
GWAGARSSNS EPSNRGGITS NGSTVTVQLA IDILRQVWIQ VLGLDHLNDQ ENDEAEELED
RLMTRSFFEL GGDSLAAIRA IALAQARGLS LSLEQFFRTS SLPEMASSAA ASMSSDVMPT
LFLFHDADGT VWKLLELARQ LPFPVIGVQA TTDSDAIAKP QSASVEELAR GYWDNIREHQ
PKGPYAFGGF SFGCRVAHEV SRLAVSQGHD ILPLILLDGL PFEVPSTHQQ VTKAKKAAAR
IRIEEYAVEA FSDELLRPLG VNYRRFCAME ETYQPYTAAQ VETGRSSEPP IWLSADLYMT
QRWNADVSQY RALGIDISTG VTLQNCTHLN MLRHPTVEVI ARHIRQRASM K
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