ID G5ALA6_HETGA Unreviewed; 387 AA.
AC G5ALA6;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Dynein regulatory complex protein 9 {ECO:0000256|ARBA:ARBA00013738};
DE AltName: Full=IQ domain-containing protein G {ECO:0000256|ARBA:ARBA00032183};
DE Flags: Fragment;
GN ORFNames=GW7_00050 {ECO:0000313|EMBL:EHA97816.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHA97816.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHA97816.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium, flagellum
CC {ECO:0000256|ARBA:ARBA00004230}. Cytoplasm, cytoskeleton, flagellum
CC axoneme {ECO:0000256|ARBA:ARBA00004611}.
CC -!- SIMILARITY: Belongs to the DRC9 family.
CC {ECO:0000256|ARBA:ARBA00008222}.
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DR EMBL; JH165776; EHA97816.1; -; Genomic_DNA.
DR AlphaFoldDB; G5ALA6; -.
DR STRING; 10181.G5ALA6; -.
DR eggNOG; ENOG502QQR7; Eukaryota.
DR InParanoid; G5ALA6; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR GO; GO:0031514; C:motile cilium; IEA:UniProtKB-KW.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR042618; IQCG.
DR PANTHER; PTHR14871; DYNEIN REGULATORY COMPLEX PROTEIN 9; 1.
DR PANTHER; PTHR14871:SF1; DYNEIN REGULATORY COMPLEX PROTEIN 9; 1.
DR Pfam; PF00612; IQ; 1.
DR SMART; SM00015; IQ; 1.
DR PROSITE; PS50096; IQ; 1.
PE 3: Inferred from homology;
KW Cell projection {ECO:0000256|ARBA:ARBA00023069};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Flagellum {ECO:0000256|ARBA:ARBA00022846};
KW Reference proteome {ECO:0000313|Proteomes:UP000006813}.
FT REGION 46..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 361..387
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 180..207
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 259..297
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 361..379
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EHA97816.1"
SQ SEQUENCE 387 AA; 45017 MW; 37DB150626151F56 CRC64;
PEAASGLSLL EVLMVSVVLE DAREQLSILG HIMPWPLERR QSTVLVSDGN NSPDKPPALL
TGRKISTPLP LKGPVSPRVR PGGQLAAKQN NIRDLAFKTP AARAIMTAET LKKMQSDRQF
FSDVIAGTMQ ELQESGTFMS LLKALQKEKE NKIHFYDVIA REEEGRKMIK SLQKQLINVK
KEQQAEVQSQ NEYIAHLKDQ LQEMKAKTNL ENHYMKRNTE LQIAQTQRKC NWTEEVLLEE
IEKVRMKTEE ENRIHMEIEM FLRKEQQRLE EKLEFWMEKF DKDTEMKQNE LNALKAAKAS
DLAHLQHLAK MIREYEEVII EDRIEKEKTR KKMEQDTLEL KSAIKLQAWW RGTVIRKEIG
GFKMPKKEKD DSKDSKGKDK DKRRGKK
//
