ID G5AS87_HETGA Unreviewed; 453 AA.
AC G5AS87;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=Chordin-like protein 2 {ECO:0000313|EMBL:EHA99893.1};
GN ORFNames=GW7_02090 {ECO:0000313|EMBL:EHA99893.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHA99893.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHA99893.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
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DR EMBL; JH166727; EHA99893.1; -; Genomic_DNA.
DR AlphaFoldDB; G5AS87; -.
DR STRING; 10181.G5AS87; -.
DR eggNOG; ENOG502QQFQ; Eukaryota.
DR InParanoid; G5AS87; -.
DR OrthoDB; 3670395at2759; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR Gene3D; 6.20.200.20; -; 1.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 2.
DR InterPro; IPR045717; CHRDL1/2.
DR InterPro; IPR001007; VWF_dom.
DR PANTHER; PTHR46303:SF3; CHORDIN-LIKE PROTEIN 2; 1.
DR PANTHER; PTHR46303; VWFC DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00093; VWC; 3.
DR SMART; SM00214; VWC; 3.
DR SUPFAM; SSF57603; FnI-like domain; 3.
DR PROSITE; PS01208; VWFC_1; 3.
DR PROSITE; PS50184; VWFC_2; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006813};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..453
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003473661"
FT DOMAIN 33..96
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DOMAIN 109..175
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DOMAIN 251..316
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT REGION 182..234
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 379..453
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 416..434
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 435..453
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 453 AA; 50140 MW; 07843E4EC50C72E6 CRC64;
MVPEVRVLSF LLGLALLWFP LDSHARARPD LFCLFHEKRY SPGESWHPYL EPQGVMYCLR
CTCSETAHVN CYQLRCPPVH CPQPVLEPQQ CCPRCVEPHT PSGLRAPPKS CQHNGTMYQH
GEIFSVRELF PGRLPNQCVL CSCTEGQIYC GLMTCPEPGC PAPFPLPDSC CQACKDGVSE
KPAGEDPAQS QRGPRRSQDP CSSEGGRKRG PGTPAPTGPS SPLGFISHRH FRPKGPGSTI
VKIVLKDTHN KACVYRGKTY SHGEVWHPVF PSFGPLPCIR CTCQDGRQYC QHVTCPAEYP
CHHPKRVAGK CCKICPEDRA DPGHSEISST RCPKAPSRVL IHTSVSPSPG SLHRFALEHE
ASDQVEIYLW KLVKDEETET QRGEVPGPRA HSQNLPLGSD QESQEAGLPE RGPELPAAHQ
HPRRLLEHLS SSDSRAEGHS QSRQSNQDFI TKT
//
