ID G5AUC7_HETGA Unreviewed; 607 AA.
AC G5AUC7;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=Leucine zipper putative tumor suppressor 1 {ECO:0000313|EMBL:EHB00638.1};
GN ORFNames=GW7_13654 {ECO:0000313|EMBL:EHB00638.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB00638.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHB00638.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
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DR EMBL; JH167028; EHB00638.1; -; Genomic_DNA.
DR AlphaFoldDB; G5AUC7; -.
DR STRING; 10181.G5AUC7; -.
DR eggNOG; ENOG502QRU7; Eukaryota.
DR InParanoid; G5AUC7; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR InterPro; IPR045329; LZTS.
DR PANTHER; PTHR19354:SF5; ZIPPER PUTATIVE TUMOR SUPPRESSOR 1-RELATED; 1.
DR PANTHER; PTHR19354; ZIPPER PUTATIVE TUMOR SUPPRESSOR 2 HOMOLOG-LIKE PROTEIN-RELATED; 1.
DR Pfam; PF06818; Fez1; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000006813}.
FT REGION 74..190
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 291..326
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 330..483
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 171..190
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 291..312
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 607 AA; 67416 MW; 150453B9767E832B CRC64;
MGSVSSLISG HGFHSKHCRA SQYKLRKPSH LKKLNRYSDG LLRFGFSQDS GHGKSSSKMG
KSEDFFYIKV SQKGRGSHRP DYTALSSGDV GGPAGVDFDP STPPKLMPFS SQLDMGSEKG
PVRPTAFKPV LPRSGAVLHS SPDSASHQLH PAPPDKSKDP EVKPGLCSGA LSDSGRNSMS
SLPTHSTSSS YQLDPLVTPV GPASRFGGSA HNIMQGILLQ DSNMTSLKTL SFSDGGSKLA
HAGKVDKGAS CVRSPISTDE CAVQELEQQL LQRGSELQKL QRSFEEKEFT SSQAFEDRAR
RSRDEVDGVE PKGGGGKLKQ AASQKSQRTQ QVLHLQVLQL QQEKRQLRQE LESLMKEQDL
LETKLRSYER EKTNFAPALE ETQWEVCQKS GEISLLKQQL KESQAEVNAK ASEILSLKAQ
LKDTRGKLEG MELRTQDLES ALRTKGLELE VCENELQRKK NEAELLREKV NLLEQELLEL
RAQATLQREG AALGPRLGAA PTFSEDIPAL QRELEQLRAE LKEERQGHDQ MSSGFQQERL
VWREEKEKVI QYQKQLLQQS YLAMYQRNQR LEKALQQLAR GEGAGEPFEI DLEGADIPYE
DIIATEI
//
