ID G5B5K3_HETGA Unreviewed; 222 AA.
AC G5B5K3;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE SubName: Full=Transmembrane protein 54 {ECO:0000313|EMBL:EHB04571.1};
GN ORFNames=GW7_11508 {ECO:0000313|EMBL:EHB04571.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB04571.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHB04571.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TMEM54 family.
CC {ECO:0000256|ARBA:ARBA00011030}.
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DR EMBL; JH168589; EHB04571.1; -; Genomic_DNA.
DR RefSeq; XP_004850944.1; XM_004850887.2.
DR AlphaFoldDB; G5B5K3; -.
DR STRING; 10181.G5B5K3; -.
DR eggNOG; ENOG502S0UN; Eukaryota.
DR InParanoid; G5B5K3; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR Bgee; ENSHGLG00000014726; Expressed in zone of skin and 8 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR020977; Beta-casein-like.
DR PANTHER; PTHR31258; KERATINOCYTE-ASSOCIATED PROTEIN 3; 1.
DR PANTHER; PTHR31258:SF2; TRANSMEMBRANE PROTEIN 54; 1.
DR Pfam; PF12304; BCLP; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006813};
KW Transmembrane {ECO:0000256|SAM:Phobius, ECO:0000313|EMBL:EHB04571.1};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 54..81
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 93..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 159..178
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 222 AA; 23490 MW; 5405714DB7427280 CRC64;
MALPTGGVSV DDFQKVLMKT GLVLVVLGHV SFIAAAILHG TVLRYVTAPH DAVALQYCVV
NIVSVTSAIV VISSGIAAIV LSRYLPSTAL RWTVFSSGVA CALLSLTCAL GLLASIAVTF
ATQGRALLAV CTFGNPDLLA LTPDCPFDPT RVYSSSLCLW GISLVLCVTE SVFAVRCIQL
AHQVLELRPW WGKSSHHTMQ ESPEPVEGHD LISCTSSVPL TL
//
