ID   G5BJK2_HETGA            Unreviewed;       627 AA.
AC   G5BJK2;
DT   14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2011, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   RecName: Full=Coiled-coil domain-containing protein 22 {ECO:0000256|ARBA:ARBA00016694};
GN   ORFNames=GW7_20099 {ECO:0000313|EMBL:EHB09463.1};
OS   Heterocephalus glaber (Naked mole rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC   Heterocephalus.
OX   NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB09463.1, ECO:0000313|Proteomes:UP000006813};
RN   [1] {ECO:0000313|EMBL:EHB09463.1, ECO:0000313|Proteomes:UP000006813}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21993625; DOI=10.1038/nature10533;
RA   Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA   Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA   Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA   Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA   Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA   Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT   "Genome sequencing reveals insights into physiology and longevity of the
RT   naked mole rat.";
RL   Nature 479:223-227(2011).
CC   -!- SIMILARITY: Belongs to the CCDC22 family.
CC       {ECO:0000256|ARBA:ARBA00006438}.
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DR   EMBL; JH170646; EHB09463.1; -; Genomic_DNA.
DR   AlphaFoldDB; G5BJK2; -.
DR   STRING; 10181.G5BJK2; -.
DR   eggNOG; KOG1937; Eukaryota.
DR   InParanoid; G5BJK2; -.
DR   Proteomes; UP000006813; Unassembled WGS sequence.
DR   InterPro; IPR008530; CCDC22.
DR   InterPro; IPR048348; CCDC22_CC.
DR   InterPro; IPR048349; CCDC22_N.
DR   PANTHER; PTHR15668:SF4; COILED-COIL DOMAIN-CONTAINING PROTEIN 22; 1.
DR   PANTHER; PTHR15668; JM1 PROTEIN; 1.
DR   Pfam; PF05667; CCDC22_CC; 1.
DR   Pfam; PF21674; CCDC22_N; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006813}.
FT   DOMAIN          1..109
FT                   /note="CCDC22 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF21674"
FT   DOMAIN          128..597
FT                   /note="CCDC22 coiled-coil"
FT                   /evidence="ECO:0000259|Pfam:PF05667"
FT   COILED          327..354
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          450..524
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   627 AA;  70517 MW;  03199BDA3AD7BF85 CRC64;
     MEEADRILIH SLRQAGTAVP PDVQTLRAFT TELVVEAVVR CLRVINPAVG SGLSPLLPVA
     MSARFRLAMS LAQACMDLGY PLELGYQNFL YPSEPDLRDL LLFLAERLPT DASEDADQPP
     GDSSILLRAI GSQIRDQLAL PWVPPLLRTP KLQRLQGSAL QQPFHTSTLV MPELSSRGEP
     REFQASPLLL PVPTQVLGPA GRAASLLESH TVQLCQHMGR DRPGDEDWVR RAPRLPTQED
     PRVPQQRLQK QLTEYLRQSW GPAGASTQAR DLGELLQAWG SGARTGAPKG SRFTHSEKFT
     FQLEPQAQTA QETDVPATAQ RPEQDIRAAQ EQELESLREQ LEGVNHSIEE VEADMKTLGI
     SLVQVETECQ QSELSTAERE QALRLKSQAV ELLPDGAANL AKLQLVVESS AQRVIHLASQ
     WEKHRVPLLA EYRHLRKLQD CREVESSRRL AEIQELHQSV RAAAEEARRK EEVYKQLVSE
     LETLPRDVSR LAYTQRILEI VGNIRKQKEE ITKILSDTKE LQKEINSLSG KLDRTFAVTD
     ELVFKDAKKD DAVRKAYKYL AALHENCSQL IQTIEDTGTI MREVRDLEEQ IEMEMSKKTL
     SNLEKICEDY RALRQENAGL LGRVREA
//