ID G5BU77_HETGA Unreviewed; 489 AA.
AC G5BU77;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=NF-kappa-B-activating protein {ECO:0000313|EMBL:EHB12838.1};
GN ORFNames=GW7_07408 {ECO:0000313|EMBL:EHB12838.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB12838.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHB12838.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
CC -!- SIMILARITY: Belongs to the NKAP family.
CC {ECO:0000256|ARBA:ARBA00009313}.
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DR EMBL; JH171897; EHB12838.1; -; Genomic_DNA.
DR AlphaFoldDB; G5BU77; -.
DR STRING; 10181.G5BU77; -.
DR InParanoid; G5BU77; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR InterPro; IPR040466; NKAP.
DR InterPro; IPR009269; NKAP_C.
DR PANTHER; PTHR13087; NF-KAPPA B ACTIVATING PROTEIN; 1.
DR PANTHER; PTHR13087:SF2; NF-KAPPA-B-ACTIVATING PROTEIN; 1.
DR Pfam; PF06047; Nkap_C; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000006813}.
FT DOMAIN 382..479
FT /note="NF-kappa-B-activating protein C-terminal"
FT /evidence="ECO:0000259|Pfam:PF06047"
FT REGION 1..386
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 89..111
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 116..139
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 181..226
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 227..243
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 272..297
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 298..326
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 489 AA; 54659 MW; 0CFDDB156A96EC4A CRC64;
MGIFPASPER PLVPPLPGHT CSDGSGVPVA QPRGRGLGLQ GKTSQFVEEP RRQSAPLSRR
FRDTPVAMAP VSRSRSPEGE ASGSRGKRRS LSKSPKPSKS SRSPRGRRSR SRSCSRSGDR
NGLSHPLSGL SQSSRNQLHR SRSRSLERPS ALWSTPFAPA CSSAYYGAYS RPFGGGDKPW
PSLLDKEREE SLRQNSDEHT PVEDEEPKKS TTSASSSEDE KKKRSTRSKE RSKKKRKKKS
SKRKDKKYSE DSDSDSDSET DSSDEDTKRR AKKAKKKEKK KKHRSKKCKK KKSKKSRKES
SASSSKDSQE EFLENLWKDQ SKAEEPSDLI GTKASKTLAF QDDKPLNYGH ALLPGEEAEE
PSDLIGPEAP KTLASQDDKP LNYGHALLPG EGAAMAEYVK AGKRIPRRGE IGLTSEEIAS
FECSGYVMSG SRHRRMEAVR LRKENQIYSA DEKRALASFN QEERRKRENK ILASFREMVY
RKTKGKDDK
//
