ID   G5BUD4_HETGA            Unreviewed;       405 AA.
AC   G5BUD4;
DT   14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2011, sequence version 1.
DT   24-JAN-2024, entry version 34.
DE   SubName: Full=DDI1-like protein 1 {ECO:0000313|EMBL:EHB12896.1};
GN   ORFNames=GW7_15566 {ECO:0000313|EMBL:EHB12896.1};
OS   Heterocephalus glaber (Naked mole rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC   Heterocephalus.
OX   NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB12896.1, ECO:0000313|Proteomes:UP000006813};
RN   [1] {ECO:0000313|EMBL:EHB12896.1, ECO:0000313|Proteomes:UP000006813}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21993625; DOI=10.1038/nature10533;
RA   Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA   Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA   Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA   Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA   Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA   Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT   "Genome sequencing reveals insights into physiology and longevity of the
RT   naked mole rat.";
RL   Nature 479:223-227(2011).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; JH171904; EHB12896.1; -; Genomic_DNA.
DR   AlphaFoldDB; G5BUD4; -.
DR   STRING; 10181.G5BUD4; -.
DR   MEROPS; A28.A01; -.
DR   eggNOG; KOG0012; Eukaryota.
DR   InParanoid; G5BUD4; -.
DR   Proteomes; UP000006813; Unassembled WGS sequence.
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   CDD; cd05479; RP_DDI; 1.
DR   Gene3D; 2.40.70.10; Acid Proteases; 1.
DR   InterPro; IPR019103; Peptidase_aspartic_DDI1-type.
DR   InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR   PANTHER; PTHR15397:SF3; DNA DAMAGE-INDUCIBLE 1 HOMOLOG 2; 1.
DR   PANTHER; PTHR15397; SODIUM-GLUCOSE COTRANSPORTER REGULATORY PROTEIN -RELATED; 1.
DR   Pfam; PF09668; Asp_protease; 1.
DR   SUPFAM; SSF50630; Acid proteases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000006813}.
FT   DOMAIN          188..311
FT                   /note="Aspartic peptidase DDI1-type"
FT                   /evidence="ECO:0000259|Pfam:PF09668"
FT   REGION          43..103
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        43..73
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        81..99
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   405 AA;  45101 MW;  6F5330E91EA72750 CRC64;
     MLITAYCVQR DLSEETFSLQ VSPDFELCNF KVLCELESRV RDNVGQTPNQ PRVDFNGIPQ
     PGTSSSQHQH QHHQPQHQQQ KQKQKRVLLA QQSHGLASGE KTASAAGLES PALIHSMLLS
     SPHDLSLLKE RNPVLAEALL SGNLETFSQV LMEQQREMAL REEERLSLYS ADPFDREAQA
     KIEEEIRQQN IEENMNIAME EAPESFGQVA MLYINCKVNG YPLKAFVDSG AQMTIMSQAC
     AEGCNIIKLV DQRWAGVAKG VGTQRIIGHV HLAQIQIEGD FLQCSFSILE EQPMDILLGL
     DMLRRHQCSI DLKKNVLVIG TTGTETYFLP EGELPSCAKL VSGTGQEEPS GKEDNNIWFH
     ITKTQRSSDH KTTVLSPSHL VPHYKDAEDT GPPDHCTGAN KVLNI
//