ID G5C0X6_HETGA Unreviewed; 366 AA.
AC G5C0X6;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE RecName: Full=SH3 domain-containing YSC84-like protein 1 {ECO:0000256|ARBA:ARBA00019109};
GN ORFNames=GW7_02788 {ECO:0000313|EMBL:EHB15187.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB15187.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHB15187.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
CC -!- SUBUNIT: Interacts with SH3D19. {ECO:0000256|ARBA:ARBA00011089}.
CC -!- SIMILARITY: Belongs to the SH3YL1 family.
CC {ECO:0000256|ARBA:ARBA00007761}.
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DR EMBL; JH172733; EHB15187.1; -; Genomic_DNA.
DR RefSeq; XP_004868357.1; XM_004868300.2.
DR AlphaFoldDB; G5C0X6; -.
DR STRING; 10181.G5C0X6; -.
DR Ensembl; ENSHGLT00000001492; ENSHGLP00000001448; ENSHGLG00000001117.
DR Ensembl; ENSHGLT00100011553; ENSHGLP00100011419; ENSHGLG00100008481.
DR GeneID; 101703830; -.
DR KEGG; hgl:101703830; -.
DR CTD; 26751; -.
DR eggNOG; KOG1843; Eukaryota.
DR InParanoid; G5C0X6; -.
DR OrthoDB; 37167at2759; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR GO; GO:0006661; P:phosphatidylinositol biosynthetic process; IEA:Ensembl.
DR GO; GO:1900027; P:regulation of ruffle assembly; IEA:Ensembl.
DR CDD; cd11841; SH3_SH3YL1_like; 1.
DR CDD; cd11525; SYLF_SH3YL1_like; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR035511; SH3YL1_SH3.
DR InterPro; IPR033643; SYLF_SH3YL1-like.
DR InterPro; IPR007461; Ysc84_actin-binding.
DR PANTHER; PTHR15629:SF2; SH3 DOMAIN-CONTAINING YSC84-LIKE PROTEIN 1; 1.
DR PANTHER; PTHR15629; SH3YL1 PROTEIN; 1.
DR Pfam; PF00018; SH3_1; 1.
DR Pfam; PF04366; Ysc84; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000006813};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 307..366
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
SQ SEQUENCE 366 AA; 39954 MW; 7909B3D4D7C7959C CRC64;
MAQRPQHATE PKSCVHAVKE ENTPMNVNNP IPSNLKSEAK KAAKILREFT EITSRNGPDK
IIPAHVIAKA KGLAILSVIK AGFLVTARGG SGIVLARLPD GKWSAPSAIG IAGLGGGFEV
GIEVSDLVII LNYDRAVEAF AKGGNLTLGG NFTVAVGPMG RNLEGNVALR SPAAVFTYCR
SRGLFAGISL EGSCLIERKE TNRKFYGQDI RAYDILFGDV PRPAQAEDLY EILDSFTEKY
EHEGQRINMR RAAREQQKAK ELPPKPALRL QQPSAPLQLD SSSQGNRHEH KLYPELSGYH
ERAGDSGRPV EVTALYSFEG QQPGDLMFQA GDKITVISKT DSHFDWWEGK LRGQTGIFPA
NYVTMN
//
