ID G5C0Z9_HETGA Unreviewed; 337 AA.
AC G5C0Z9;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE SubName: Full=p2Y purinoceptor 14 {ECO:0000313|EMBL:EHB15210.1};
GN Name=P2RY14 {ECO:0000313|EMBL:JAN95968.1};
GN ORFNames=GW7_20771 {ECO:0000313|EMBL:EHB15210.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB15210.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHB15210.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
RN [2] {ECO:0000313|EMBL:JAN95968.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Ovary {ECO:0000313|EMBL:JAN95968.1};
RA Bens M., Sahm A., Jahn N., Morhart M., Holtze S., Hildebrandt T.B.,
RA Platzer M., Szafranski K.;
RT "FRAMA: From RNA-seq data to annotated mRNA assemblies.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; JH172735; EHB15210.1; -; Genomic_DNA.
DR EMBL; GEBF01007664; JAN95968.1; -; Transcribed_RNA.
DR RefSeq; XP_004834520.1; XM_004834463.2.
DR AlphaFoldDB; G5C0Z9; -.
DR STRING; 10181.G5C0Z9; -.
DR Ensembl; ENSHGLT00100043908; ENSHGLP00100044903; ENSHGLG00100048084.
DR Ensembl; ENSHGLT00100047318; ENSHGLP00100056654; ENSHGLG00100048084.
DR Ensembl; ENSHGLT00100048177; ENSHGLP00100041730; ENSHGLG00100048084.
DR Ensembl; ENSHGLT00100049689; ENSHGLP00100051017; ENSHGLG00100048084.
DR Ensembl; ENSHGLT00100055012; ENSHGLP00100052350; ENSHGLG00100048084.
DR Ensembl; ENSHGLT00100069215; ENSHGLP00100048881; ENSHGLG00100048084.
DR GeneID; 101703159; -.
DR KEGG; hgl:101703159; -.
DR CTD; 9934; -.
DR eggNOG; ENOG502R537; Eukaryota.
DR InParanoid; G5C0Z9; -.
DR OMA; FVHTVNY; -.
DR OrthoDB; 5390357at2759; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR Bgee; ENSHGLG00000016668; Expressed in ovary and 5 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0045028; F:G protein-coupled purinergic nucleotide receptor activity; IEA:InterPro.
DR CDD; cd15149; 7tmA_P2Y14; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR005466; P2Y14_rcpt.
DR PANTHER; PTHR24233:SF3; P2Y PURINOCEPTOR 14; 1.
DR PANTHER; PTHR24233; P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR01157; P2YPURNOCPTR.
DR PRINTS; PR01655; UDPGLUCOSER.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000006813};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 24..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 56..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 96..117
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..159
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 189..214
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 235..252
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 279..299
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 39..295
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
SQ SEQUENCE 337 AA; 38876 MW; 6751142B345859A1 CRC64;
MLNSTTTQPP DLPCSKNTLI TQQIIPVLYC VVFITGILLN GVSGWVFLYV PSSKSFIIYL
KNIVVADFLM GLTFPFKILG DSGLGPWQLN VFVCRVSAVL FYVNMYVSIV FFGLISFDRY
YKIVKPLSTS FIQSVNYSKL LSVVVWILML LLAVPNIILT NQSVREVTKI QCMQLKNELG
RKWHKASNYI FVGIFWAVFL LLIIFYTAIT RKIFKSHLKY RRNSISVKRK SSRNIFSIMI
VFFVCFVPYH IARIPYTKSQ TEAHYSCQSK ELLLYVKEFT LLLSAANVCL DPIIYFFLCQ
PFREILCKKL HISLKTHDLA TFKTRRGNII HESTDTL
//
