ID G5CDP0_9BURK Unreviewed; 220 AA.
AC G5CDP0;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=DNA topoisomerase (ATP-hydrolyzing) {ECO:0000256|ARBA:ARBA00012895};
DE EC=5.6.2.2 {ECO:0000256|ARBA:ARBA00012895};
DE Flags: Fragment;
GN Name=gyrB {ECO:0000313|EMBL:AEP39790.1};
OS Burkholderia sp. SD3165B.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia.
OX NCBI_TaxID=1090468 {ECO:0000313|EMBL:AEP39790.1};
RN [1] {ECO:0000313|EMBL:AEP39790.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=SD3165B {ECO:0000313|EMBL:AEP39790.1};
RX PubMed=21915326; DOI=10.1371/journal.pone.0024430;
RA Lemaire B., Vandamme P., Merckx V., Smets E., Dessein S.;
RT "Bacterial Leaf Symbiosis in Angiosperms: Host Specificity without Co-
RT Speciation.";
RL PLoS ONE 6:E24430-E24430(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP-dependent breakage, passage and rejoining of double-
CC stranded DNA.; EC=5.6.2.2; Evidence={ECO:0000256|ARBA:ARBA00000185};
CC -!- SIMILARITY: Belongs to the type II topoisomerase GyrB family.
CC {ECO:0000256|ARBA:ARBA00010708}.
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DR EMBL; JN053987; AEP39790.1; -; Genomic_DNA.
DR AlphaFoldDB; G5CDP0; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003918; F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity; IEA:UniProtKB-EC.
DR GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR CDD; cd16928; HATPase_GyrB-like; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR001241; Topo_IIA.
DR PANTHER; PTHR45866:SF1; DNA GYRASE SUBUNIT B, MITOCHONDRIAL; 1.
DR PANTHER; PTHR45866; DNA GYRASE/TOPOISOMERASE SUBUNIT B; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR PRINTS; PR00418; TPI2FAMILY.
DR SMART; SM00433; TOP2c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Topoisomerase {ECO:0000256|ARBA:ARBA00023029}.
FT DOMAIN 3..97
FT /note="Histidine kinase/HSP90-like ATPase"
FT /evidence="ECO:0000259|Pfam:PF02518"
FT REGION 22..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AEP39790.1"
FT NON_TER 220
FT /evidence="ECO:0000313|EMBL:AEP39790.1"
SQ SEQUENCE 220 AA; 24504 MW; CF7428C10C814503 CRC64;
LAGYCDDIHV VIHADNSISV TDNGRGVPTG LKRDDKHDPK RSAAEIVMTE LHAGGKFDQN
SYKVSGGLHG VGVSCVNALS EWLRLTVRRD SKKHFMEFSR GVVQNREIVE EDGVQYSPMP
VVGDTENRGT EVHFLADATI FGNVEFHYDI LAKRMRELSF LNNGVWIRLT DQRTGKEDDF
AFAGGVKGFV EYINKAKQVL HPTVFHATGE RENVTVEVAM
//
