ID   G5DTL4_CEBPY            Unreviewed;      1520 AA.
AC   G5DTL4;
DT   14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2011, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=Abnormal spindle-like microcephaly-associated protein {ECO:0000313|EMBL:AEQ58809.1};
DE   Flags: Fragment;
GN   Name=ASPM {ECO:0000313|EMBL:AEQ58809.1};
OS   Cebuella pygmaea (Pygmy marmoset) (Callithrix pygmaea).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC   Callitrichinae; Cebuella.
OX   NCBI_TaxID=9493 {ECO:0000313|EMBL:AEQ58809.1};
RN   [1] {ECO:0000313|EMBL:AEQ58809.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Cep592 {ECO:0000313|EMBL:AEQ58809.1};
RA   Montgomery S.H., Mundy N.I.;
RT   "Evolution of ASPM is associated with both increases and decreases in brain
RT   size in primates.";
RL   Evolution 0:0-0(2011).
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DR   EMBL; JN701480; AEQ58809.1; -; Genomic_DNA.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   Gene3D; 1.20.5.190; -; 29.
DR   InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR22590:SF4; ABNORMAL SPINDLE-LIKE MICROCEPHALY-ASSOCIATED PROTEIN; 1.
DR   PANTHER; PTHR22590; UNCHARACTERIZED; 1.
DR   Pfam; PF00612; IQ; 32.
DR   SMART; SM00015; IQ; 49.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 17.
DR   PROSITE; PS50096; IQ; 28.
PE   4: Predicted;
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AEQ58809.1"
FT   NON_TER         1520
FT                   /evidence="ECO:0000313|EMBL:AEQ58809.1"
SQ   SEQUENCE   1520 AA;  183887 MW;  DB9B3BF17AD674FD CRC64;
     VLQSRIRMII AVTSYKRYLW ATVTIQRHWR AYLRRKQDQQ RYEMLKSSSL IIQAMFRRWK
     RRKMQLQVKA TITLQRAFRE WHLRKRAKEE KSAIVIQSWY RMHKQLRKYV YVRSCVVIIQ
     KRFRCFQAQR LYKRRRESIL TIQKYYRAYL KGKIERTNYL QKRAAAIQLQ AAFRRLKAHN
     LHRQNRAACV IQSYWRMRQD RVRFLNLKKI IIKLQAHVRP LQQLQKYKKI KKAAVIIQTH
     FQAYIFARKV LASYQKTRSA VIVLQSAYRG MQARKMYIHI LTSVIKIQSY YRAYVSKKEF
     LSLKNAXIKL QSIVKMKQTR KQYLHLRATA VFIQQCYRSK KLAAQKREEY MQMRESCIKL
     QAFVRGYLVR KQMRLQRKAV TSLQSYFRMR KTRQYYLKMY KAVIIVQNYY HSYKAQVNQR
     KNFLQVKKAA TCLQAAYRGY KVRQLIKQQS IAAVKIQSAF RGYSNRVKYQ SVLQSIIKIQ
     RWYRAYKTLS DIRTHFLKTK AAVISLQSAY RGWKVRKQIR REHQAAVKIQ SAFRMAKAQK
     QFRLFKTAAL VIQQHLRAWS AGRKQRMEYI ELRHSVLMLQ SMWKGKTLRR RLQRRHKCAV
     IIQSYYRMHV QQKKWKIMKK AALLIQKYYR AYSTGREQHH LYLKTKAAVV TLQSAYRGMK
     VRKRIKDCNK AAVTIQSKYR AYKTKKKYAA YRASAIIIQR WYRGIKITNH QYKEYHSLKK
     TAIKIQAVYR GIRVRRHIQH MHRAATFINA MFKMHHSRIR YHTMRKAAIV IQVRYRAYYQ
     GKMQRENYLX ILRAVNVLQA NFRGVRVRQT LRKLQIAATV IQSNYRRYRE QTYFNKLKKI
     TRTVQQRYRA VKKRNILFQR YNKLRHSVIH IQAIFRGLKA RRHLKTMHIA ATLIQRRFRT
     LMMRRRFLSL KKTAIWIQRR YRAHLCTKHH LQFLQLQNAA IKLQSSYRRW MIRKKMREMH
     RAATFIQATF RMHRVHMRYQ ALKQASVVIQ QHYQANRAAK LQRQHYLRQR HSAVILQAAF
     RGMKTRRHLK SMHSSAILIQ SRFRSLLVRR RFISLKKAAI FIQRKYRATI CAKHKLHQFL
     QLRKAAIIIQ SSYRRLMVKK KLQEMHRAAV LIQATFRMHR TYVTFQTWKH ASILIQQHYR
     TYRASKLQTE NNTKQWYSAV IVQAAYRGMK ARQLLREKHK AAIIIQSTYR MYRQYCLYQN
     LQWATKIIQE KYRANKKKHK ALQHNELKKA ETCVQASFQD MNIKKLIQEQ HQTSIIIQKH
     CKAFKIKKHY LHLREPVVSI QRRYRKLTAV HTQAVICIQS YYRGFKVRRD IQNMHLAATQ
     IQSFYRMHRA KVDYQTKKTA IVVIQNYYRL YVRVKTERRS FLAVQKSVRT SQAAFRGMKV
     RQNLKNVSQE KMAAIVKRSA LYCYRSKAQY EAVRSEGVLI QEWDKAACLA GSQEAGDHSQ
     SRAAVTIQEA FHRMITRKLE TRRCAALQIQ FFLQMAVYRR RFLQQKRAAV TLQHYFRTWQ
     TRKQFLLYRK AAVVLQNHYR
//