ID G5E2Y2_9PIPI Unreviewed; 196 AA.
AC G5E2Y2;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=ethanolamine-phosphate cytidylyltransferase {ECO:0000256|ARBA:ARBA00024221};
DE EC=2.7.7.14 {ECO:0000256|ARBA:ARBA00024221};
DE AltName: Full=CTP:phosphoethanolamine cytidylyltransferase {ECO:0000256|ARBA:ARBA00031473};
DE Flags: Fragment;
OS Hymenochirus curtipes (western dwarf clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Pipinae; Hymenochirus.
OX NCBI_TaxID=8362 {ECO:0000313|EMBL:AEQ18485.1};
RN [1] {ECO:0000313|EMBL:AEQ18485.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Liver {ECO:0000313|EMBL:AEQ18485.1};
RA Chain F.J.J., Evans B.J., Dushoff J.;
RT "The odds of duplicate gene persistence after polyploidization.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- PATHWAY: Phospholipid metabolism; phosphatidylethanolamine
CC biosynthesis; phosphatidylethanolamine from ethanolamine: step 2/3.
CC {ECO:0000256|ARBA:ARBA00024191}.
CC -!- SIMILARITY: Belongs to the cytidylyltransferase family.
CC {ECO:0000256|ARBA:ARBA00010101}.
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DR EMBL; JP287746; AEQ18485.1; -; mRNA.
DR AlphaFoldDB; G5E2Y2; -.
DR UniPathway; UPA00558; UER00742.
DR GO; GO:0004306; F:ethanolamine-phosphate cytidylyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0006646; P:phosphatidylethanolamine biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.50.620; HUPs; 2.
DR InterPro; IPR004821; Cyt_trans-like.
DR InterPro; IPR044608; Ect1/PCYT2.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR NCBIfam; TIGR00125; cyt_tran_rel; 1.
DR PANTHER; PTHR45780; ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE; 1.
DR PANTHER; PTHR45780:SF2; ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE; 1.
DR Pfam; PF01467; CTP_transf_like; 2.
DR SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
PE 2: Evidence at transcript level;
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000313|EMBL:AEQ18485.1};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:AEQ18485.1}.
FT DOMAIN 2..50
FT /note="Cytidyltransferase-like"
FT /evidence="ECO:0000259|Pfam:PF01467"
FT DOMAIN 104..193
FT /note="Cytidyltransferase-like"
FT /evidence="ECO:0000259|Pfam:PF01467"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AEQ18485.1"
FT NON_TER 196
FT /evidence="ECO:0000313|EMBL:AEQ18485.1"
SQ SEQUENCE 196 AA; 22103 MW; C91368D7FC92F7B3 CRC64;
IKWVDEIVPG APYVTTLETL DKYNCDFCVH GNDITLTVRM LLMTKAHHSV EVTLDYQQHR
DNLSKDAGGR SPWTGVSQFL QTSQKIMQFA SGKEPAPGDT IIYVAGAFDL FHIGHIDFLE
KVHSMAEKPY VILLHFDQEV NHYKGKNYPI MNIHERTLSV LACRYVAEVV IGAPYSVSAD
LLDHFKVDLV CHGKTD
//
