ID   G5GGW0_9FIRM            Unreviewed;       556 AA.
AC   G5GGW0;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   24-JAN-2024, entry version 40.
DE   RecName: Full=NlpC/P60 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=HMPREF9333_00800 {ECO:0000313|EMBL:EHI56018.1};
OS   Johnsonella ignava ATCC 51276.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC   Johnsonella.
OX   NCBI_TaxID=679200 {ECO:0000313|EMBL:EHI56018.1, ECO:0000313|Proteomes:UP000003011};
RN   [1] {ECO:0000313|EMBL:EHI56018.1, ECO:0000313|Proteomes:UP000003011}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51276 {ECO:0000313|EMBL:EHI56018.1,
RC   ECO:0000313|Proteomes:UP000003011};
RG   The Broad Institute Genome Sequencing Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Izard J., Blanton J.M.,
RA   Baranova O.V., Dewhirst F.E., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA   Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C., Freedman E.,
RA   Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA   Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA   Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA   Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Johnsonella ignava ATCC 51276.";
RL   Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase C40 family.
CC       {ECO:0000256|ARBA:ARBA00007074}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EHI56018.1}.
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DR   EMBL; ACZL01000014; EHI56018.1; -; Genomic_DNA.
DR   RefSeq; WP_005540013.1; NZ_JH378830.1.
DR   AlphaFoldDB; G5GGW0; -.
DR   STRING; 679200.HMPREF9333_00800; -.
DR   PATRIC; fig|679200.3.peg.844; -.
DR   eggNOG; COG0791; Bacteria.
DR   eggNOG; COG3103; Bacteria.
DR   HOGENOM; CLU_016043_13_0_9; -.
DR   Proteomes; UP000003011; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.1720.10; endopeptidase domain like (from Nostoc punctiforme); 1.
DR   Gene3D; 2.30.30.40; SH3 Domains; 4.
DR   InterPro; IPR000064; NLP_P60_dom.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR003646; SH3-like_bac-type.
DR   PANTHER; PTHR34408; FAMILY PROTEIN, PUTATIVE-RELATED; 1.
DR   PANTHER; PTHR34408:SF1; GLYCOSYL HYDROLASE FAMILY 19 DOMAIN-CONTAINING PROTEIN HI_1415; 1.
DR   Pfam; PF00877; NLPC_P60; 1.
DR   Pfam; PF08239; SH3_3; 4.
DR   SMART; SM00287; SH3b; 4.
DR   SUPFAM; SSF54001; Cysteine proteinases; 1.
DR   PROSITE; PS51935; NLPC_P60; 1.
DR   PROSITE; PS51781; SH3B; 2.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003011};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        57..78
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          123..191
FT                   /note="SH3b"
FT                   /evidence="ECO:0000259|PROSITE:PS51781"
FT   DOMAIN          353..416
FT                   /note="SH3b"
FT                   /evidence="ECO:0000259|PROSITE:PS51781"
FT   DOMAIN          435..556
FT                   /note="NlpC/P60"
FT                   /evidence="ECO:0000259|PROSITE:PS51935"
SQ   SEQUENCE   556 AA;  61894 MW;  140982557AB49C4D CRC64;
     MKKKKKFKFF LKPPKFTKGF GINFDLINPV LLIKKIPRPS DIAAMPKWKR HIFIQKCSIT
     AGAILILIFF TVIGVRAFTS GGIFSTATMS NARKSSSSDA MSEEEKRRLD EEAKATAEIE
     GVIDSYNQIA IAKVDGYLNI REKPDKFADV IGKLYDGGAC DILNTDNNEW YLVKSGNIEG
     YVHKTFLVTG DDAKQLARSE VRDMAVINAD KLNIRAMPAI DAEIVSNAYM GERYEIISNE
     NGWIQVPEGY MSAEYAEIKK TLAEARKLDL RSMVLDLYDN LGMSDVQGYL NVREEPSENG
     KIIGKMTSKA GGEILESLDG WYKIRSGKIT GYVKSDYIRT GQAAKDEAIA EAQLMAIVNT
     DVLNVRAEPN TDAKIWTQIS NSEKYIVVSQ QDGWVEIELE NDNNAFVSTD FVDVRYALNE
     AIKFSPVEEA AIAAQSRRAQ IVNYALQFLG NRYVWGGTSL TNGCDCSGFT MKILGNYGVS
     LPHYSGSQAQ MGKKISSDQM RPGDLIFYSN SRGTINHVAM YIGNGQIVHA ASRRSGIKIS
     QWNYRKPTVI RDMLGD
//