ID G5IB85_9CLOT Unreviewed; 722 AA.
AC G5IB85;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=HAMP domain-containing protein {ECO:0000259|PROSITE:PS50885};
GN ORFNames=HMPREF9473_00807 {ECO:0000313|EMBL:EHI61192.1};
OS Hungatella hathewayi WAL-18680.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Hungatella.
OX NCBI_TaxID=742737 {ECO:0000313|EMBL:EHI61192.1, ECO:0000313|Proteomes:UP000005384};
RN [1] {ECO:0000313|EMBL:EHI61192.1, ECO:0000313|Proteomes:UP000005384}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WAL-18680 {ECO:0000313|EMBL:EHI61192.1,
RC ECO:0000313|Proteomes:UP000005384};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Finegold S.M., Summanen P.H.,
RA Molitoris D.R., Song M., Daigneault M., Allen-Vercoe E., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Clostridium hathewayi WAL-18680.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHI61192.1}.
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DR EMBL; ADLN01000006; EHI61192.1; -; Genomic_DNA.
DR RefSeq; WP_006778793.1; NZ_JH379027.1.
DR AlphaFoldDB; G5IB85; -.
DR PATRIC; fig|742737.3.peg.802; -.
DR HOGENOM; CLU_020306_1_0_9; -.
DR Proteomes; UP000005384; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd12913; PDC1_MCP_like; 1.
DR CDD; cd12912; PDC2_MCP_like; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR PANTHER; PTHR43156:SF2; MULTIDOMAIN REGULATORY PROTEIN RV1364C; 1.
DR PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF07228; SpoIIE; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00331; PP2C_SIG; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF81606; PP2C-like; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005384};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 381..404
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 409..461
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
SQ SEQUENCE 722 AA; 79499 MW; 2E1AF6E87F810096 CRC64;
MKKVVRHSIR YKITAMALGV SVLAVVLCGA VAVFGMRNMI REAATASQSL GETAAYDSRT
ALVGQAQDGL KEQVKQKAEL TEERLLNIAG QVETTAGYMS GVYQNPQRYL PRPVEKPAMK
NAGKWALQYS LVEDVDYEAV QEEIDLAGNL YHMVAPLCEG NDTVSSIYFS SANGFMISYD
KNSDNMFEGK TAGQPAELFV DHYDPRDRDW YQEAVETGKS VFTETYLDTF GRLLISCAAP
VYGRGTKPVG VLAMDILIED INHSVVSARV GNRGYVFLMN HDGYVVSAPD LAVVDGTYES
VNLMEQEEMK TLAERMASGQ SGLISFVKDG EDVFAAFEPI APTGWSMAMV LPQEEVIAPA
VVSYENILEN TSRANAQMEG IVHSAMVGVL ALSALILLGV LFFAEIRSRK ITEPITRLTK
EVAVIGQGNL DHTVEMHTGD ELETLGNAFN QMTKSLGEYM ENLAEVTADR ERIATELNVA
STIQSSMLPC IFPAFPDQKD FDIYADMHPA KAVGGDFYDF FKTDENHLWV VIADVSGKGV
PAALFMVIAK TMLKNYAGFG ASPAEVLAIV NDRLCENNEA DMFVTVFIGV FEISSGIFTF
SNAGHNYPLL YRKGGAFDWL KSSPDFVIAG MEGMKFRDNR VAINPGDRLF LYTDGVTEAL
NRKEELYGDD RLIETLNRPE TREMSIDELV TYMKADLASY ADGAEQADDI TMLVLEIREG
EK
//
