ID   G5JYN3_9STRE            Unreviewed;       737 AA.
AC   G5JYN3;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   27-MAR-2024, entry version 54.
DE   SubName: Full=Gram-positive signal peptide protein, YSIRK family {ECO:0000313|EMBL:EHJ52697.1};
GN   ORFNames=STRMA_0295 {ECO:0000313|EMBL:EHJ52697.1};
OS   Streptococcus macacae NCTC 11558.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=764298 {ECO:0000313|EMBL:EHJ52697.1, ECO:0000313|Proteomes:UP000003573};
RN   [1] {ECO:0000313|EMBL:EHJ52697.1, ECO:0000313|Proteomes:UP000003573}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCTC 11558 {ECO:0000313|EMBL:EHJ52697.1,
RC   ECO:0000313|Proteomes:UP000003573};
RX   PubMed=24625962; DOI=10.1093/gbe/evu048;
RA   Richards V.P., Palmer S.R., Pavinski Bitar P.D., Qin X., Weinstock G.M.,
RA   Highlander S.K., Town C.D., Burne R.A., Stanhope M.J.;
RT   "Phylogenomics and the dynamic genome evolution of the genus
RT   Streptococcus.";
RL   Genome Biol. Evol. 6:741-753(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EHJ52697.1}.
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DR   EMBL; AEUW02000001; EHJ52697.1; -; Genomic_DNA.
DR   RefSeq; WP_003081030.1; NZ_UHFV01000002.1.
DR   AlphaFoldDB; G5JYN3; -.
DR   eggNOG; COG4099; Bacteria.
DR   eggNOG; COG5263; Bacteria.
DR   OrthoDB; 9764953at2; -.
DR   Proteomes; UP000003573; Unassembled WGS sequence.
DR   GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
DR   GO; GO:0004806; F:triglyceride lipase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   Gene3D; 2.10.270.10; Cholin Binding; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR018337; Cell_wall/Cho-bd_repeat.
DR   InterPro; IPR041172; EstA_Ig-like_N.
DR   InterPro; IPR001375; Peptidase_S9.
DR   InterPro; IPR005877; YSIRK_signal_dom.
DR   NCBIfam; TIGR01168; YSIRK_signal; 1.
DR   PANTHER; PTHR43037:SF5; FERULOYL ESTERASE B; 1.
DR   PANTHER; PTHR43037; UNNAMED PRODUCT-RELATED; 1.
DR   Pfam; PF19127; Choline_bind_3; 2.
DR   Pfam; PF18435; EstA_Ig_like; 1.
DR   Pfam; PF00326; Peptidase_S9; 1.
DR   Pfam; PF04650; YSIRK_signal; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   SUPFAM; SSF69360; Cell wall binding repeat; 1.
PE   4: Predicted;
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..36
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           37..737
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003479565"
FT   DOMAIN          4..29
FT                   /note="YSIRK Gram-positive signal peptide"
FT                   /evidence="ECO:0000259|Pfam:PF04650"
FT   DOMAIN          317..422
FT                   /note="Esterase Ig-like N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF18435"
FT   DOMAIN          538..615
FT                   /note="Peptidase S9 prolyl oligopeptidase catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF00326"
FT   REGION          58..160
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   737 AA;  81312 MW;  95954E31BB7A6605 CRC64;
     MKFEKKEHYR LRKLKFGLTS VTIAASLFGI TTIAKANDKA AAEQASTTVT QVQEASKQTW
     STQAKTNETV SQNAQTTTLA NELSTAANTP STSTVNDAAK TKQQYAVTEA SSNSQQTTTA
     TTAASTSDQK RPQTKGKSQS QPSTARQTVS ENDSSHLTNT FVDDGQGNWY YLGSDGKNVT
     GSQIIDGKTM YFGQDGKQVK GGFAKDTDGN NHYYDQNDGS MWTDRFVNVQ GNWYYLNHNG
     TPVTGKVSLN GQNLYFNPDG SQVKGQFIQE NGVSYYYDEN SGDLLKNTKR IINGAVYQFD
     DNGRVTTNDK VEVVKSSIVV DSYEFGPAVS KIVLQLNHKV TTDVIHTAAT VTTAGVQRKI
     LNSYVSDAAG HVVYFDNSPY VTLELDVPYD PNDSSKNASP FIFDAQSFRN KWVDHYTVKL
     ENLQVKTGNS NSSQTISSEQ DTINNRLLLT TNRFSERGSY GNYHYAAYRP ANTNSSQKRP
     LLIWLHGVGE VGTDVNIPLL ASNVVRLTED PIQSHFTSTG KGDQKGAYVL ALQSPTPWNK
     DQTADLMKAI NAYVESHPDI DSHRIYLAGV SNGGGMTLDM GVAYPHYFAA LVPIAASYNN
     QLTDNNSQIT ANAWKSLKNQ PMWLIHTRAD QAISADTSVL PFYKKMLENG AQNKWLSYYE
     TNVGNHYSGV IYNGHWSWIY FLNDQVKGVQ NSDNAKSWPG LTGMVATNST YGGDAKANVN
     GEIYNNIFDW LNRQQRG
//