ID   G5R8F1_SALSE            Unreviewed;       518 AA.
AC   G5R8F1;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   27-MAR-2024, entry version 45.
DE   SubName: Full=5'-nucleotidase {ECO:0000313|EMBL:EHC79561.1};
GN   ORFNames=LTSESEN_6068 {ECO:0000313|EMBL:EHC79561.1};
OS   Salmonella enterica subsp. enterica serovar Senftenberg str. A4-543.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=913082 {ECO:0000313|EMBL:EHC79561.1, ECO:0000313|Proteomes:UP000005065};
RN   [1] {ECO:0000313|EMBL:EHC79561.1, ECO:0000313|Proteomes:UP000005065}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=A4-543 {ECO:0000313|EMBL:EHC79561.1,
RC   ECO:0000313|Proteomes:UP000005065};
RX   PubMed=21859443; DOI=10.1186/1471-2164-12-425;
RA   den Bakker H.C., Moreno Switt A.I., Govoni G., Cummings C.A., Ranieri M.L.,
RA   Degoricija L., Hoelzer K., Rodriguez-Rivera L.D., Brown S., Bolchacova E.,
RA   Furtado M.R., Wiedmann M.;
RT   "Genome sequencing reveals diversification of virulence factor content and
RT   possible host adaptation in distinct subpopulations of Salmonella
RT   enterica.";
RL   BMC Genomics 12:425-425(2011).
CC   -!- SIMILARITY: Belongs to the 5'-nucleotidase family.
CC       {ECO:0000256|ARBA:ARBA00006654, ECO:0000256|RuleBase:RU362119}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EHC79561.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AFCU01001918; EHC79561.1; -; Genomic_DNA.
DR   AlphaFoldDB; G5R8F1; -.
DR   PATRIC; fig|913082.3.peg.4759; -.
DR   BioCyc; SENT913082:G120J-638-MONOMER; -.
DR   Proteomes; UP000005065; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0008252; F:nucleotidase activity; IEA:UniProt.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0009166; P:nucleotide catabolic process; IEA:InterPro.
DR   CDD; cd00845; MPP_UshA_N_like; 1.
DR   Gene3D; 3.60.21.10; -; 1.
DR   Gene3D; 3.90.780.10; 5'-Nucleotidase, C-terminal domain; 1.
DR   InterPro; IPR008334; 5'-Nucleotdase_C.
DR   InterPro; IPR036907; 5'-Nucleotdase_C_sf.
DR   InterPro; IPR006146; 5'-Nucleotdase_CS.
DR   InterPro; IPR006179; 5_nucleotidase/apyrase.
DR   InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR   InterPro; IPR029052; Metallo-depent_PP-like.
DR   PANTHER; PTHR11575; 5'-NUCLEOTIDASE-RELATED; 1.
DR   PANTHER; PTHR11575:SF46; PROTEIN USHA; 1.
DR   Pfam; PF02872; 5_nucleotid_C; 1.
DR   Pfam; PF00149; Metallophos; 1.
DR   PRINTS; PR01607; APYRASEFAMLY.
DR   SUPFAM; SSF55816; 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain; 1.
DR   SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR   PROSITE; PS00786; 5_NUCLEOTIDASE_2; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|RuleBase:RU362119};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|RuleBase:RU362119}; Signal {ECO:0000256|RuleBase:RU362119}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|RuleBase:RU362119"
FT   CHAIN           21..518
FT                   /evidence="ECO:0000256|RuleBase:RU362119"
FT                   /id="PRO_5005132477"
FT   DOMAIN          24..252
FT                   /note="Calcineurin-like phosphoesterase"
FT                   /evidence="ECO:0000259|Pfam:PF00149"
FT   DOMAIN          330..476
FT                   /note="5'-Nucleotidase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02872"
SQ   SEQUENCE   518 AA;  56553 MW;  A5DE4DCE9BBC0602 CRC64;
     MKVKLLAAGI LFTLPFWACA KDVTIIYTND LHAHVEPYKV PWIADGKRDI GGWANITTLV
     KQEKAKNKAT WFFDAGDYFT GPYISSLTKG KAIIDILNTM QYDAATIGNH EFDHGWDNTL
     LQLSRAKFPI VQGNIFYEDS SKSFWDKPYT IVEKDGVKIG VIGLHGVFAF NDTVSAATRV
     GIEARDEIKW LQRYIDELKG KVDLTVALIH EGTPARQSSM GNTDVRRALD KDIQTASQVK
     GLDILITGHA HVGTPEPIKV GNTLILSTDS GGIDVGKLVL DYQEKPHQFT VKNFELKTIF
     ADEWKPDPQT KQVIDGWNKK LDKVVQQTVA QSPVELTRAY GESSSLGNLA ADALLFTAGK
     DTQLALTNSG GIRNEIPAGA VTMGAVISTF PFPNELVTMD LTGKQLRSLM EHGAGLSNGV
     LQVSKGLEMK YDSSKPVGQR VTVLTLNGKP IDDATVYHIA TNSFLADGGD GFAAFTEGQA
     RNTSGGYYVS NAIVDYFKAG NTITDEQLKG MRVADVKK
//