ID G5ZXR6_9PROT Unreviewed; 479 AA.
AC G5ZXR6;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=Putative Zn-dependent protease-like protein {ECO:0000313|EMBL:EHI49247.1};
GN ORFNames=HIMB100_00008170 {ECO:0000313|EMBL:EHI49247.1};
OS SAR116 cluster alpha proteobacterium HIMB100.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; SAR116 cluster.
OX NCBI_TaxID=909943 {ECO:0000313|EMBL:EHI49247.1, ECO:0000313|Proteomes:UP000004261};
RN [1] {ECO:0000313|EMBL:EHI49247.1, ECO:0000313|Proteomes:UP000004261}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=strain HIMB100 {ECO:0000313|Proteomes:UP000004261};
RX PubMed=22675578; DOI=10.4056/sigs.1854551;
RA Grote J., Bayindirli C., Bergauer K., Carpintero de Moraes P., Chen H.,
RA D'Ambrosio L., Edwards B., Fernandez-Gomez B., Hamisi M., Logares R.,
RA Nguyen D., Rii Y.M., Saeck E., Schutte C., Widner B., Church M.J.,
RA Steward G.F., Karl D.M., Delong E.F., Eppley J.M., Schuster S.C.,
RA Kyrpides N.C., Rappe M.S.;
RT "Draft genome sequence of strain HIMB100, a cultured representative of the
RT SAR116 clade of marine Alphaproteobacteria.";
RL Stand. Genomic Sci. 5:269-278(2011).
CC -!- SIMILARITY: Belongs to the peptidase U62 family.
CC {ECO:0000256|ARBA:ARBA00005836}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHI49247.1}.
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DR EMBL; AFXB01000006; EHI49247.1; -; Genomic_DNA.
DR AlphaFoldDB; G5ZXR6; -.
DR STRING; 909943.HIMB100_00008170; -.
DR PATRIC; fig|909943.3.peg.827; -.
DR eggNOG; COG0312; Bacteria.
DR OrthoDB; 9803213at2; -.
DR Proteomes; UP000004261; Unassembled WGS sequence.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.30.2290.10; PmbA/TldD superfamily; 1.
DR InterPro; IPR045569; Metalloprtase-TldD/E_C.
DR InterPro; IPR045570; Metalloprtase-TldD/E_cen_dom.
DR InterPro; IPR002510; Metalloprtase-TldD/E_N.
DR InterPro; IPR025502; TldD.
DR InterPro; IPR035068; TldD/PmbA_N.
DR InterPro; IPR036059; TldD/PmbA_sf.
DR PANTHER; PTHR30624:SF4; METALLOPROTEASE TLDD; 1.
DR PANTHER; PTHR30624; UNCHARACTERIZED PROTEIN TLDD AND PMBA; 1.
DR Pfam; PF01523; PmbA_TldD_1st; 1.
DR Pfam; PF19290; PmbA_TldD_2nd; 1.
DR Pfam; PF19289; PmbA_TldD_3rd; 1.
DR PIRSF; PIRSF004919; TldD; 1.
DR SUPFAM; SSF111283; Putative modulator of DNA gyrase, PmbA/TldD; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000313|EMBL:EHI49247.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000004261}.
FT DOMAIN 37..99
FT /note="Metalloprotease TldD/E N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01523"
FT DOMAIN 125..234
FT /note="Metalloprotease TldD/E central"
FT /evidence="ECO:0000259|Pfam:PF19290"
FT DOMAIN 242..475
FT /note="Metalloprotease TldD/E C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19289"
SQ SEQUENCE 479 AA; 50685 MW; C0EA1FDBF34E9286 CRC64;
MDLLQQTDNV FFTSTGLDRD RTMKIVASCL EGADDGDLFL EMKHAEMLAF DDGRLKTATY
DQSAGFGLRA IVGEADAFAH AGELSEAALT RAAETVSAVA SGHSGQLAVA PEAGRNLSLY
SDANPLNQTA FEDKVELLQK IDAYAREKDP RVKQVSASIA GSWQAVQIIR PDGTRYADIR
PLVRLNVAVV AEKNGRMESG SSGTGGRFMF DRYLQDDIWQ AEVDEALRIA MLNLDSVGAP
AGEMEIVLGS GWPGVMLHEA VGHGLEGDFN RKGTSVFSGR IGEQVAAKGV TVVDDGTMQD
RRGSITIDDE GTESARNVLI EDGVLKGYMQ DRQNARLMGV HATGNGRRQS YAHLPMPRMT
NTFMENGSYA ADEIVASMKK GIYAVNFGGG QVDITSGKFV FSASEAYLVE NGKIGAPVKG
ATLIGSGPDA MSKITMIGDD LALDRGVGTC GKAGQSVPVG VGQPTLKMGG ITVGGTEAA
//
