ID G6ED10_9SPHN Unreviewed; 308 AA.
AC G6ED10;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:EHJ60849.1};
GN ORFNames=NSU_2231 {ECO:0000313|EMBL:EHJ60849.1};
OS Novosphingobium pentaromativorans US6-1.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Novosphingobium.
OX NCBI_TaxID=1088721 {ECO:0000313|EMBL:EHJ60849.1, ECO:0000313|Proteomes:UP000004030};
RN [1] {ECO:0000313|EMBL:EHJ60849.1, ECO:0000313|Proteomes:UP000004030}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=US6-1 {ECO:0000313|EMBL:EHJ60849.1,
RC ECO:0000313|Proteomes:UP000004030};
RX PubMed=22275104; DOI=10.1128/JB.06476-11;
RA Luo Y.R., Kang S.G., Kim S.J., Kim M.R., Li N., Lee J.H., Kwon K.K.;
RT "Genome sequence of benzo(a)pyrene-degrading bacterium Novosphingobium
RT pentaromativorans US6-1.";
RL J. Bacteriol. 194:907-907(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHJ60849.1}.
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DR EMBL; AGFM01000030; EHJ60849.1; -; Genomic_DNA.
DR RefSeq; WP_007013146.1; NZ_CP009291.1.
DR AlphaFoldDB; G6ED10; -.
DR STRING; 1088721.JI59_08930; -.
DR KEGG; npn:JI59_08930; -.
DR PATRIC; fig|1088721.3.peg.2211; -.
DR eggNOG; COG0287; Bacteria.
DR OrthoDB; 9802008at2; -.
DR Proteomes; UP000004030; Unassembled WGS sequence.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:InterPro.
DR GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR046825; PDH_C.
DR InterPro; IPR046826; PDH_N.
DR InterPro; IPR003099; Prephen_DH.
DR PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR Pfam; PF20463; PDH_C; 1.
DR Pfam; PF02153; PDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51176; PDH_ADH; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000004030}.
FT DOMAIN 4..292
FT /note="Prephenate/arogenate dehydrogenase"
FT /evidence="ECO:0000259|PROSITE:PS51176"
FT REGION 286..308
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 308 AA; 33570 MW; 25730D12B99E5CD0 CRC64;
MSFEKVAIIG LGLQGGSIGL ATQEFLPEVQ TSGFDLDPAT RARAADRGLV HQVCETAAEA
VRDADLVIFC VPPGVMGEAA LDVRDALRKD ALISDVGSCK QSIAAALREA LPDHYVIPAH
PVAGTENSGP DAGFAHLFRN RWCIVTPPEH TDLVKLSQLV EFWEALGANV EIMDAQHHDL
VLAVTSHLPH LIAYTIVGTA SDLEDVTQSE VIKYSAGGFR DFTRIAASDP TMWRDVFLTN
KEAVLTMLQR FTEDLTALQR AIRVGDGDAL FEQFARTRAI RRSIIQEGQD DSRPDFGRGD
HENGTKKI
//
