ID G7EC62_9GAMM Unreviewed; 930 AA.
AC G7EC62;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Multicomponent K+:H+ antiporter subunit A {ECO:0000313|EMBL:GAA58485.1};
GN Name=phaA {ECO:0000313|EMBL:GAA58485.1};
GN ORFNames=P20652_0340 {ECO:0000313|EMBL:GAA58485.1};
OS Pseudoalteromonas sp. BSi20652.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Pseudoalteromonadaceae; Pseudoalteromonas.
OX NCBI_TaxID=388384 {ECO:0000313|EMBL:GAA58485.1, ECO:0000313|Proteomes:UP000005499};
RN [1] {ECO:0000313|Proteomes:UP000005499}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bsi20652 {ECO:0000313|Proteomes:UP000005499};
RX PubMed=22275105; DOI=10.1128/JB.06427-11;
RA Bian F., Xie B.B., Qin Q.L., Shu Y.L., Zhang X.Y., Yu Y., Chen B.,
RA Chen X.L., Zhou B.C., Zhang Y.Z.;
RT "Genome sequences of six Pseudoalteromonas strains isolated from Arctic sea
RT ice.";
RL J. Bacteriol. 194:908-909(2012).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU000320}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU000320}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAA58485.1}.
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DR EMBL; BADT01000023; GAA58485.1; -; Genomic_DNA.
DR RefSeq; WP_008165881.1; NZ_BADT01000023.1.
DR AlphaFoldDB; G7EC62; -.
DR OrthoDB; 9811798at2; -.
DR Proteomes; UP000005499; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR InterPro; IPR007182; MnhB.
DR InterPro; IPR025383; MrpA_C/MbhD.
DR InterPro; IPR046806; MrpA_C/MbhE.
DR InterPro; IPR001750; ND/Mrp_mem.
DR InterPro; IPR001516; Proton_antipo_N.
DR PANTHER; PTHR43373:SF1; ANTIPORTER SUBUNIT MNHA2-RELATED; 1.
DR PANTHER; PTHR43373; NA(+)/H(+) ANTIPORTER SUBUNIT; 1.
DR Pfam; PF13244; MbhD; 1.
DR Pfam; PF20501; MbhE; 1.
DR Pfam; PF04039; MnhB; 1.
DR Pfam; PF00361; Proton_antipo_M; 1.
DR Pfam; PF00662; Proton_antipo_N; 1.
DR PRINTS; PR01434; NADHDHGNASE5.
PE 4: Predicted;
KW Antiport {ECO:0000256|ARBA:ARBA00022449};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000320};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 77..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 109..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 132..151
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 163..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 208..230
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 242..264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 270..291
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 298..316
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 322..343
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 364..389
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 409..427
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 459..482
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 502..521
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 568..585
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 601..620
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 625..645
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 651..673
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 685..707
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 748..767
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 787..807
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 813..830
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 851..869
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 891..916
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 62..105
FT /note="NADH-Ubiquinone oxidoreductase (complex I) chain 5
FT N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00662"
FT DOMAIN 126..401
FT /note="NADH:quinone oxidoreductase/Mrp antiporter membrane
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF00361"
FT DOMAIN 609..674
FT /note="MrpA C-terminal/MbhD"
FT /evidence="ECO:0000259|Pfam:PF13244"
FT DOMAIN 684..773
FT /note="MrpA C-terminal/MbhE"
FT /evidence="ECO:0000259|Pfam:PF20501"
FT DOMAIN 789..910
FT /note="Na+/H+ antiporter MnhB subunit-related protein"
FT /evidence="ECO:0000259|Pfam:PF04039"
SQ SEQUENCE 930 AA; 101214 MW; A2D3803A0424507E CRC64;
MTLLWIPLLS LIGSVISACT GKLSRNLSTS LTALAPLVAL GITLYHAPAV LAGETIRYSL
AWIPSIGLDL SLRLDGLSLL FMFMILGIGL LVILYTRYYL SANDSMAKLY SYLMLFMTAM
LGIVMSNNVI QLWLFWELTS ISSFLLISFW WHKSEARKGA RMALAVTGAG GLALLAGLML
LGDIVGSYDL DVILASKAII QSHDLYEVAL VLVLLGAFTK SAQFPFHFWL PHAMAAPTPV
SAYLHSATMV KAGIFLLARF YPALAGTETW FILVGLTGLT TLLFGAYIAL FKHDLKGLLA
YSTISHLGLI TLLLGLDTEL ATVAAIFHII NHATFKASLF MAVGIIDHET GTRDMRKLNG
MWRFLPYTAT LAMVAAASMA GVPLLNGFLS KEMFFAETLH QQVLGSMSWL IPVLATIAGA
FSVAYSARFI HDVFFNGDPI DLPRTPHEPP RYMRVPIEIL VVICLLVGMF PHFMVGGILS
AASSAVLGKA MPDYEVALWH GFNLPLLMSA MAVAGGLFIY INRKYLFQFQ ASLPPLNAKK
TFERAVLSTI SWCQLKISHI ENGSLQRYLV VMLGVVLLCA GWPLFEMQEL AGAMPRTPVD
VHNAIGASLL IIGAIATVIW HRSRVVALLM ISIVGLMVSV AFTRFSAPDL ALTQLTVEVA
TVILLMLALF FLPQYTPKES SSLRILRDLS IASTLGVVVA SICYALLTRP LNSISDFFIA
NAKTGGGGTN VVNVILVDFR GFDTLGEITV LGIAALGIFK VLSRIPLYMP ASDGEGRPWA
RERHPILLAN ISHSLLPLAL LVSAYIFLRG HNLPGGGFIA GLVTSIAFIL QYMAHGSSWI
NERFGVNYRK IIASGIGIAL FTGVGSWFFD KPFLTTWFDY FDIPFIGKTE LASAIVFDLG
VYLTVVGATL MILASLGNMT ADTQRKEVNI
//
