ID G7EYA4_9GAMM Unreviewed; 223 AA.
AC G7EYA4;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE RecName: Full=tRNA (guanine(46)-N(7))-methyltransferase {ECO:0000256|ARBA:ARBA00011977};
DE EC=2.1.1.33 {ECO:0000256|ARBA:ARBA00011977};
GN ORFNames=P20311_3709 {ECO:0000313|EMBL:GAA65877.1};
OS Pseudoalteromonas sp. BSi20311.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Pseudoalteromonadaceae; Pseudoalteromonas.
OX NCBI_TaxID=383911 {ECO:0000313|EMBL:GAA65877.1, ECO:0000313|Proteomes:UP000005146};
RN [1] {ECO:0000313|Proteomes:UP000005146}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BSi20311 {ECO:0000313|Proteomes:UP000005146};
RX PubMed=22275105; DOI=10.1128/JB.06427-11;
RA Bian F., Xie B.B., Qin Q.L., Shu Y.L., Zhang X.Y., Yu Y., Chen B.,
RA Chen X.L., Zhou B.C., Zhang Y.Z.;
RT "Genome sequences of six Pseudoalteromonas strains isolated from Arctic sea
RT ice.";
RL J. Bacteriol. 194:908-909(2012).
CC -!- FUNCTION: Catalyzes the formation of N(7)-methylguanine at position 46
CC (m7G46) in tRNA. {ECO:0000256|ARBA:ARBA00003015}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=guanosine(46) in tRNA + S-adenosyl-L-methionine = N(7)-
CC methylguanosine(46) in tRNA + S-adenosyl-L-homocysteine;
CC Xref=Rhea:RHEA:42708, Rhea:RHEA-COMP:10188, Rhea:RHEA-COMP:10189,
CC ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, ChEBI:CHEBI:74269,
CC ChEBI:CHEBI:74480; EC=2.1.1.33;
CC Evidence={ECO:0000256|ARBA:ARBA00000142};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAA65877.1}.
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DR EMBL; BADU01000190; GAA65877.1; -; Genomic_DNA.
DR RefSeq; WP_008115619.1; NZ_BADU01000190.1.
DR AlphaFoldDB; G7EYA4; -.
DR Proteomes; UP000005146; Unassembled WGS sequence.
DR GO; GO:0008176; F:tRNA (guanine(46)-N7)-methyltransferase activity; IEA:InterPro.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR003358; tRNA_(Gua-N-7)_MeTrfase_Trmb.
DR Pfam; PF02390; Methyltransf_4; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51625; SAM_MT_TRMB; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:GAA65877.1};
KW Transferase {ECO:0000313|EMBL:GAA65877.1}.
SQ SEQUENCE 223 AA; 25287 MW; 66C6BDF104502E67 CRC64;
MSDANSRSIV SNQAGLHEKL DEIVNKHLQA EFKKPIATHT QTAFDEVNAK VQAFNGPLIL
DSCCGVGEST ANLAKRHPEA LVVGIDKSSH RLDKHDVEYK QTESGQYILV QADLNDFWRL
AVAANWQPTH HYLLYPNPWP KSKHIQRRWH GAAIFPFIVK LGGLLEVRSN WDIYVKEFAR
ALELAGYPCQ TALFESDEAI TPFERKYWAS GQQSHRLAIN INN
//
