ID G7KHF6_MEDTR Unreviewed; 1052 AA.
AC G7KHF6;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=LRR receptor-like kinase {ECO:0000313|EMBL:AET00008.1};
GN OrderedLocusNames=MTR_5g087370 {ECO:0000313|EMBL:AET00008.1};
OS Medicago truncatula (Barrel medic) (Medicago tribuloides).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Trifolieae; Medicago.
OX NCBI_TaxID=3880 {ECO:0000313|EMBL:AET00008.1, ECO:0000313|Proteomes:UP000002051};
RN [1] {ECO:0000313|EMBL:AET00008.1, ECO:0000313|Proteomes:UP000002051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A17 {ECO:0000313|EMBL:AET00008.1}, and cv. Jemalong A17
RC {ECO:0000313|EnsemblPlants:AET00008,
RC ECO:0000313|Proteomes:UP000002051};
RX PubMed=22089132; DOI=10.1038/nature10625;
RA Young N.D., Debelle F., Oldroyd G.E., Geurts R., Cannon S.B., Udvardi M.K.,
RA Benedito V.A., Mayer K.F., Gouzy J., Schoof H., Van de Peer Y., Proost S.,
RA Cook D.R., Meyers B.C., Spannagl M., Cheung F., De Mita S.,
RA Krishnakumar V., Gundlach H., Zhou S., Mudge J., Bharti A.K., Murray J.D.,
RA Naoumkina M.A., Rosen B., Silverstein K.A., Tang H., Rombauts S.,
RA Zhao P.X., Zhou P., Barbe V., Bardou P., Bechner M., Bellec A., Berger A.,
RA Berges H., Bidwell S., Bisseling T., Choisne N., Couloux A., Denny R.,
RA Deshpande S., Dai X., Doyle J.J., Dudez A.M., Farmer A.D., Fouteau S.,
RA Franken C., Gibelin C., Gish J., Goldstein S., Gonzalez A.J., Green P.J.,
RA Hallab A., Hartog M., Hua A., Humphray S.J., Jeong D.H., Jing Y.,
RA Jocker A., Kenton S.M., Kim D.J., Klee K., Lai H., Lang C., Lin S.,
RA Macmil S.L., Magdelenat G., Matthews L., McCorrison J., Monaghan E.L.,
RA Mun J.H., Najar F.Z., Nicholson C., Noirot C., O'Bleness M., Paule C.R.,
RA Poulain J., Prion F., Qin B., Qu C., Retzel E.F., Riddle C., Sallet E.,
RA Samain S., Samson N., Sanders I., Saurat O., Scarpelli C., Schiex T.,
RA Segurens B., Severin A.J., Sherrier D.J., Shi R., Sims S., Singer S.R.,
RA Sinharoy S., Sterck L., Viollet A., Wang B.B., Wang K., Wang M., Wang X.,
RA Warfsmann J., Weissenbach J., White D.D., White J.D., Wiley G.B.,
RA Wincker P., Xing Y., Yang L., Yao Z., Ying F., Zhai J., Zhou L., Zuber A.,
RA Denarie J., Dixon R.A., May G.D., Schwartz D.C., Rogers J., Quetier F.,
RA Town C.D., Roe B.A.;
RT "The Medicago genome provides insight into the evolution of rhizobial
RT symbioses.";
RL Nature 480:520-524(2011).
RN [2] {ECO:0000313|EMBL:AET00008.1, ECO:0000313|Proteomes:UP000002051}
RP GENOME REANNOTATION.
RC STRAIN=cv. Jemalong A17 {ECO:0000313|EnsemblPlants:AET00008,
RC ECO:0000313|Proteomes:UP000002051};
RX PubMed=24767513; DOI=10.1186/1471-2164-15-312;
RA Tang H., Krishnakumar V., Bidwell S., Rosen B., Chan A., Zhou S.,
RA Gentzbittel L., Childs K.L., Yandell M., Gundlach H., Mayer K.F.,
RA Schwartz D.C., Town C.D.;
RT "An improved genome release (version Mt4.0) for the model legume Medicago
RT truncatula.";
RL BMC Genomics 15:312-312(2014).
RN [3] {ECO:0000313|EnsemblPlants:AET00008}
RP IDENTIFICATION.
RC STRAIN=cv. Jemalong A17 {ECO:0000313|EnsemblPlants:AET00008};
RG EnsemblPlants;
RL Submitted (APR-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC kinase family. {ECO:0000256|ARBA:ARBA00008684}.
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DR EMBL; CM001221; AET00008.1; -; Genomic_DNA.
DR RefSeq; XP_003617049.1; XM_003617001.1.
DR AlphaFoldDB; G7KHF6; -.
DR PaxDb; 3880-AET00008; -.
DR EnsemblPlants; AET00008; AET00008; MTR_5g087370.
DR Gramene; AET00008; AET00008; MTR_5g087370.
DR eggNOG; ENOG502QUAH; Eukaryota.
DR HOGENOM; CLU_000288_22_1_1; -.
DR OMA; YWIGNDY; -.
DR Proteomes; UP000002051; Chromosome 5.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 5.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR48054:SF13; OS08G0446200 PROTEIN; 1.
DR PANTHER; PTHR48054; RECEPTOR KINASE-LIKE PROTEIN XA21; 1.
DR Pfam; PF00560; LRR_1; 5.
DR Pfam; PF08263; LRRNT_2; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF52058; L domain-like; 2.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:AET00008.1};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Receptor {ECO:0000313|EMBL:AET00008.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002051};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 653..946
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 681
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 1052 AA; 117472 MW; 757D4DAB817E77C2 CRC64;
MKRTSYSSRI ITHLLTISFL HGATALNYDG LTLLSLMTDW TIVPPIIDSS WNPSDSNPCS
WVGVRCDHAN NLISLNLPSQ GIFGRLGPEI GNLYHLQNLL LFGNAFSGKV PSELSNCSLL
QNLELSENRF SGKIPYTLKN LQKLQFMALA SNMLTGEIPD SLFQIQSLEE VSLHSNLLSG
PIPTNIGNLT RLLRLYLYGN QLSGTIPTSL GNCSKLEDLE FSFNRLRGEI PVSVWRISSL
VHILVHNNSL SRELPFEMTK LKYLKNISLF DNQFSGVTPQ SLGINSSIVK LDCMNNKFSG
NIPPNICFGK HLLVLNMGIN QLQGNIPSDV GRCETLMRLF LNENNFTGSL PDFESNLNLK
YMDMSKNKIS GRIPSSLGNC TNLTYINLSR NKFARLIPSQ LGNLVNLVIL DLSNNLEGPL
PLQLSNCTKM DHFDVGFNFL NGSVPSSLGS WRNITTLILR ENYFTGGIPG FLPNFNNLRE
LQLGGNLFGG DIPSGIDWIG LQQLQSLDIS LNNLTGSIDA LGGLVSLIEV NISFNLFHGS
VPKGLMNLLN SSPSSFMGNP LLCCSSCIKS VYVNLCVDKS TGHIGISELK IVTIVLGSSI
CISVPLLIII RMYLNRDELK RTSDLNKRIS NKRGGGRKLP DLHKQVLEAT ENLNDRYIIG
GGAHGIVYKA IICETVCAVK KVEFRRNKQK RLSITRNEVE VLGMFKHRNL IKCLDYWIGN
DYGLILYEFM ENGSLHDILH EKKPPPPLTW DVRCKIAVGI AQGLLYLHYD CVPPIVHRDI
KPKNILVNDN MEPIISDFGT ALCKKLSEDS NSHSETRKML SSRVVGTPGY IAPENAYDVV
PGRKSDVYSY GVVLLEIITR KKLLVPSMND EAEETHIVTW ARSVMMETGK IENIVDPYLV
SAFPNSITLV KQVNAVLSLA LQCTEKDPRK RTTMKVVIGF YNKNLFKMRY DEVQYGDGLV
VELMGNGKIQ YKKVFGIANL VVPKITYAWS SLIFRPSITG PILTKPFNWF FLSHWGQYRH
LQKSLYLQTK SYSSYSISIN TNQTEASFQI SE
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