ID G7M083_9CLOT Unreviewed; 484 AA.
AC G7M083;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Transcriptional regulator, GntR family with aminotransferase domain containing protein {ECO:0000313|EMBL:EHI98788.1};
GN ORFNames=CDLVIII_2125 {ECO:0000313|EMBL:EHI98788.1};
OS Clostridium sp. DL-VIII.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=641107 {ECO:0000313|EMBL:EHI98788.1, ECO:0000313|Proteomes:UP000005106};
RN [1] {ECO:0000313|EMBL:EHI98788.1, ECO:0000313|Proteomes:UP000005106}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DL-VIII {ECO:0000313|EMBL:EHI98788.1,
RC ECO:0000313|Proteomes:UP000005106};
RX PubMed=23929491;
RA Taghavi S., Izquierdo J.A., van der Lelie D.;
RT "Complete Genome Sequence of Clostridium sp. Strain DL-VIII, a Novel
RT Solventogenic Clostridium Species Isolated from Anaerobic Sludge.";
RL Genome Announc. 1:e00605-e00613(2013).
CC -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC pyridoxal-phosphate-dependent aminotransferase family.
CC {ECO:0000256|ARBA:ARBA00005384}.
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DR EMBL; CM001240; EHI98788.1; -; Genomic_DNA.
DR RefSeq; WP_009169466.1; NZ_CM001240.1.
DR AlphaFoldDB; G7M083; -.
DR STRING; 641107.CDLVIII_2125; -.
DR eggNOG; COG1167; Bacteria.
DR HOGENOM; CLU_017584_0_1_9; -.
DR Proteomes; UP000005106; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00609; AAT_like; 1.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46577; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR PANTHER; PTHR46577:SF1; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR Pfam; PF00392; GntR; 1.
DR PRINTS; PR00035; HTHGNTR.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 3: Inferred from homology;
KW Aminotransferase {ECO:0000313|EMBL:EHI98788.1};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000005106};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000313|EMBL:EHI98788.1}.
FT DOMAIN 10..78
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
SQ SEQUENCE 484 AA; 55410 MW; 0BD61C849CDCE4AE CRC64;
MIVLDINLEA PLYLQIYKQL KEQIISGEIS EGQKLPSTRK LSTSLNVSRN TVENAYMQLS
SEGYIKSKAG SGFIAQKLDT PTILKQEKID IRTSDFSKSN IIDNNINLSD YNPYSGDGYD
YKYNFEYGKL SSEDFPLRIW KRVSNKCLST VNSEDMTSYS SSTGEIDLQK EIMNYLKASR
GVSCTPSQII ISSGSEYCLS LLSQLFRGSF DEIAVEDPGY SGAKDIFINN GYKAIPISLE
DDGINVNELE TTKARIVYTT PSHQFPTGVV IPIAKRLKLL DWAKRKNGII IEDDYDSEFR
YNSKPIPSMQ SIDSNDSVIY IGTFSKCFSP SLRMNYMVLP KQWLERYYRH FKMYQTPVPL
IHQKIMQQFM HLGHFERHLH KIYLINKRKH DILIQTIQNL MGHNVSIYVK NAGLHILLQV
NNGLTEEELI NKAKDHGVKV YPVSFFWIKK ENYSNNMVLL GFGGMLENDI IEGIKLLNKA
WFTS
//
