ID G7M8I2_9CLOT Unreviewed; 331 AA.
AC G7M8I2;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE SubName: Full=Cobalamin (Vitamin B12) biosynthesis CbiM protein {ECO:0000313|EMBL:EHJ00937.1};
GN ORFNames=CDLVIII_4425 {ECO:0000313|EMBL:EHJ00937.1};
OS Clostridium sp. DL-VIII.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=641107 {ECO:0000313|EMBL:EHJ00937.1, ECO:0000313|Proteomes:UP000005106};
RN [1] {ECO:0000313|EMBL:EHJ00937.1, ECO:0000313|Proteomes:UP000005106}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DL-VIII {ECO:0000313|EMBL:EHJ00937.1,
RC ECO:0000313|Proteomes:UP000005106};
RX PubMed=23929491;
RA Taghavi S., Izquierdo J.A., van der Lelie D.;
RT "Complete Genome Sequence of Clostridium sp. Strain DL-VIII, a Novel
RT Solventogenic Clostridium Species Isolated from Anaerobic Sludge.";
RL Genome Announc. 1:e00605-e00613(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CM001240; EHJ00937.1; -; Genomic_DNA.
DR RefSeq; WP_009171588.1; NZ_CM001240.1.
DR AlphaFoldDB; G7M8I2; -.
DR STRING; 641107.CDLVIII_4425; -.
DR eggNOG; COG0310; Bacteria.
DR HOGENOM; CLU_052508_2_0_9; -.
DR Proteomes; UP000005106; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0000041; P:transition metal ion transport; IEA:InterPro.
DR Gene3D; 1.10.1760.20; -; 1.
DR InterPro; IPR002751; CbiM/NikMN.
DR InterPro; IPR025937; PDGLE_dom.
DR PANTHER; PTHR34229; METAL TRANSPORT PROTEIN HI_1621-RELATED; 1.
DR PANTHER; PTHR34229:SF1; METAL TRANSPORT PROTEIN HI_1621-RELATED; 1.
DR Pfam; PF01891; CbiM; 1.
DR Pfam; PF13190; PDGLE; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005106};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 7..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 40..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 72..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 103..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..159
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 190..212
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 232..253
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 300..321
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 230..323
FT /note="PDGLE"
FT /evidence="ECO:0000259|Pfam:PF13190"
SQ SEQUENCE 331 AA; 34989 MW; 990125035817018F CRC64;
MHIPDNYLSP ATCAVIGAVM IPVWAKSIKT VKKEITKKKM PLMGIGASLS FLTMMFNVPL
PGGTTGHAVG GTLLAILLGP EAACISITVA LLIQALLFGD GGVLAFGANS FNMAFIIPFV
GYYIYKFLKE RIKSERGEYI GALIGSYVGI NAGALFASIE LGIQPLLFKD AAGMPLYCPY
PLSISIPAML IPHLAVAGIL EAIITIGVLS FIRKVSPDIV YDGSAKKTKP IYALIIALIC
LSPLGLLATG TAWGEWGTDE INSVVVGGKA LGFVPKGMEN GFNFSALMRD YSVQGMPDSF
GYILSAIAGV AIFLIVFRII ASMRKDNGIN G
//
