ID   G7M986_9CLOT            Unreviewed;       554 AA.
AC   G7M986;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   24-JAN-2024, entry version 40.
DE   SubName: Full=UBA/THIF-type NAD/FAD binding protein {ECO:0000313|EMBL:EHJ01953.1};
GN   ORFNames=CDLVIII_5479 {ECO:0000313|EMBL:EHJ01953.1};
OS   Clostridium sp. DL-VIII.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=641107 {ECO:0000313|EMBL:EHJ01953.1, ECO:0000313|Proteomes:UP000005106};
RN   [1] {ECO:0000313|EMBL:EHJ01953.1, ECO:0000313|Proteomes:UP000005106}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DL-VIII {ECO:0000313|EMBL:EHJ01953.1,
RC   ECO:0000313|Proteomes:UP000005106};
RX   PubMed=23929491;
RA   Taghavi S., Izquierdo J.A., van der Lelie D.;
RT   "Complete Genome Sequence of Clostridium sp. Strain DL-VIII, a Novel
RT   Solventogenic Clostridium Species Isolated from Anaerobic Sludge.";
RL   Genome Announc. 1:e00605-e00613(2013).
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DR   EMBL; CM001240; EHJ01953.1; -; Genomic_DNA.
DR   RefSeq; WP_009172591.1; NZ_CM001240.1.
DR   AlphaFoldDB; G7M986; -.
DR   STRING; 641107.CDLVIII_5479; -.
DR   eggNOG; COG0476; Bacteria.
DR   HOGENOM; CLU_019556_0_0_9; -.
DR   Proteomes; UP000005106; Chromosome.
DR   GO; GO:0008641; F:ubiquitin-like modifier activating enzyme activity; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR032701; Prok-E2_B_dom.
DR   InterPro; IPR045886; ThiF/MoeB/HesA.
DR   InterPro; IPR000594; ThiF_NAD_FAD-bd.
DR   InterPro; IPR035985; Ubiquitin-activating_enz.
DR   PANTHER; PTHR43267; TRNA THREONYLCARBAMOYLADENOSINE DEHYDRATASE; 1.
DR   PANTHER; PTHR43267:SF1; TRNA THREONYLCARBAMOYLADENOSINE DEHYDRATASE; 1.
DR   Pfam; PF14461; Prok-E2_B; 1.
DR   Pfam; PF00899; ThiF; 1.
DR   SUPFAM; SSF69572; Activating enzymes of the ubiquitin-like proteins; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000005106}.
FT   DOMAIN          33..136
FT                   /note="Prokaryotic E2 family B"
FT                   /evidence="ECO:0000259|Pfam:PF14461"
FT   DOMAIN          312..403
FT                   /note="THIF-type NAD/FAD binding fold"
FT                   /evidence="ECO:0000259|Pfam:PF00899"
SQ   SEQUENCE   554 AA;  64808 MW;  AF2B86F33384B8D5 CRC64;
     MMDVLLKEIE KYLDDNGYEC IEIDNPDGKY LFIDININGN DIRLKCMFTH AFPYGFPKIS
     ILQEFYSKYG LLPHVDNDGV ICTFDTNKVY PNFNKPKEAV LECIKKSEKI LLDGINGNNR
     EDFEEEFKAY WELESEIIGE VIFEPDDKDK ILYCYTSKNR FIYLAEDEEK LKNYLKYAHI
     ADIRKVKITK ALYLPLENNW CCPPFPQNNK DIIELLSKEK NFNRYLEYLR KYNDEHIIIF
     SQVVNNKMCL AGWRHKRGKS VKGLRNINIF PKYLYYNVNG SQKIEKISVS QLNHTRIYER
     GGDGYIKTKR LISVVGCGSI GSYLIKNLVD LGINNFKIID KETLSTDNIA RHYCGAINVG
     ISKVDAIKSE LITHYPDMNC ESIKQDVFSV IEDRIEIFNQ CDYNFIVVGN IPIEAKFMEL
     LKNGDIVKPT IIIWVEPYII GAHAIIIQNR QDLFNLLYDK DYNFKEKVLI DGEKYIKREA
     GCQSTFLPYS AFEVQQCLSD ILDYVNQNIF EKGKKENFLL TWVGRIDLAR KRHMKISDKW
     IGSENRKLEI RRLN
//