ID G7MQ62_MACMU Unreviewed; 1206 AA.
AC G7MQ62;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=SAM and SH3 domain containing 1 {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=EGK_15271 {ECO:0000313|EMBL:EHH18626.1};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|EMBL:EHH18626.1};
RN [1] {ECO:0000313|EMBL:EHH18626.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CR-5 {ECO:0000313|EMBL:EHH18626.1};
RX PubMed=22002653; DOI=10.1038/nbt.1992;
RA Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q.,
RA Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z.,
RA Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y.,
RA Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X.,
RA Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W.,
RA Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.;
RT "Genome sequencing and comparison of two nonhuman primate animal models,
RT the cynomolgus and Chinese rhesus macaques.";
RL Nat. Biotechnol. 29:1019-1023(2011).
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DR EMBL; CM001256; EHH18626.1; -; Genomic_DNA.
DR AlphaFoldDB; G7MQ62; -.
DR HOGENOM; CLU_281404_0_0_1; -.
DR Proteomes; UP000013456; Chromosome 4.
DR CDD; cd09559; SAM_SASH1_repeat1; 1.
DR CDD; cd09492; SAM_SASH1_repeat2; 1.
DR CDD; cd11967; SH3_SASH1; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 2.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR037627; SASH1_SAM_repeat1.
DR InterPro; IPR037630; SASH1_SAM_repeat2.
DR InterPro; IPR035720; SASH1_SH3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR021090; SPIDER.
DR PANTHER; PTHR12301:SF3; SAM AND SH3 DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR12301; SAM-DOMAIN, SH3 AND NUCLEAR LOCALIZATION SIGNALS PROTEIN RELATED; 1.
DR Pfam; PF00536; SAM_1; 1.
DR Pfam; PF07647; SAM_2; 1.
DR Pfam; PF07653; SH3_2; 1.
DR Pfam; PF12485; SLY; 1.
DR SMART; SM00454; SAM; 2.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 2.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 2.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 508..569
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 587..651
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 1136..1200
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 172..211
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 270..298
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 403..527
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 570..593
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 667..730
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 798..837
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 865..884
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 930..1024
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 284..298
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 463..489
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 490..507
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 667..723
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 823..837
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 989..1019
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EHH18626.1"
FT NON_TER 1206
FT /evidence="ECO:0000313|EMBL:EHH18626.1"
SQ SEQUENCE 1206 AA; 132678 MW; 335215A8C445BD95 CRC64;
DVMGILDGSL GNIDDLAQQY ADYYNTCFSD VCERMEELRK RRVSQDLDVE KPDASPTSLQ
LRSQIEESLG FCSAVSTPEV ERKNPLHKSN SEDNAVGKGD WKKKNKYFWQ NFRKNQKGIM
RQTSKGEDVG YVASEITMSD EERIQLMMMV KEKMITIEEA LARLKEYEAQ HRQSAALDPT
DWPDGSYPTF DGSSNCNSRE QSDDETEESV KFKRLHKLVN STRRVRKKLI RVEEMKKPST
EGGEEHVFEN SPVLDERSAL YSGVHKKPFF FDGSPEKPPE DDSDSLTTSP SSSSLDTWGA
GRKLVKTFSK GESRGLIKPP KKMGTFFSYP EEEKAQKVSR SLTEGEMKKS LGSLSHGRTC
SFGGFDLTNR SLHVGSNNSD PMGKEGDFVY KEVIKSPTAS RISLGKKVKS VKETMRKRMS
KKYSSSVSEQ DSGLDGMPGS PPPSQPDPEH LDKPKLKAGG SVESLRSSLS GQSSMSGQTV
STTDSSASNR ESVKSEDGDD EEPPYRGPFC GRARVHTDFT PSPYDTDSLK LKKGDIIDII
SKPPMGTWMG LLNNKVGTFK FIYVDVLSED EEKPKRPTRR RRKGRPPQPK SVEDLLDRIN
LKEHMPTFLF NGYEDLDTFK LLEEEDLDEL NIRDPEHRAV LLTAVELLQE YDSNSDQSGS
QEKLLVDSQG LSGCSPRDSG CYESSENLEN GKTRKASLLS AKSSAEPNLK SFSRNQLGNY
PTLPLTKSGD ALKQGQEEGR LGGGLAPDMS KSCDPPGVTG LNKNRRSLPV SICRSCETLE
GPQTVDTWPR SHSLDDLQAE SGAEQDVPTE VTEPPPQIVP KVPQKMTASS TKAQPLERDS
AVDNALLLTQ SKRFSEPQKL TTKKLEGSIA ASGRSLSPPQ CLPRNYDAQP PGAKHGLART
PLEGHRIGHE FEGTHHPLGT KEGVDAEQRV PEARTQPKIP SQPPPVPAKK SRERLANGLY
PVPMGPGGTL PSPDAPCLPV KRGSPTSPTS PSDCPPALAP RPLSGQAPGS PPSTRPPPWL
SELPENTSLQ EHGVKLGPAL TRKVSCARGV DLEMLTENKL HAEGIDLTEE PYSDKHGRCG
IPEALVQRYA EDLDQPERDV AINMDQIRVK QLRKQHRMAI PSGGLTEICR KPVSPGCISS
VSDWLISIGL PMYASTLSTA GFSTLSQVPS LSHTCLQEAG ITEERHIRKL LSAARLFKLP
PGPEAM
//
