ID   G7NBY0_MACMU            Unreviewed;       711 AA.
AC   G7NBY0;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   22-FEB-2023, entry version 32.
DE   RecName: Full=ATP-grasp domain-containing protein {ECO:0000259|PROSITE:PS50975};
GN   ORFNames=EGK_05938 {ECO:0000313|EMBL:EHH22630.1};
OS   Macaca mulatta (Rhesus macaque).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9544 {ECO:0000313|EMBL:EHH22630.1};
RN   [1] {ECO:0000313|EMBL:EHH22630.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CR-5 {ECO:0000313|EMBL:EHH22630.1};
RX   PubMed=22002653; DOI=10.1038/nbt.1992;
RA   Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q.,
RA   Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z.,
RA   Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y.,
RA   Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X.,
RA   Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W.,
RA   Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.;
RT   "Genome sequencing and comparison of two nonhuman primate animal models,
RT   the cynomolgus and Chinese rhesus macaques.";
RL   Nat. Biotechnol. 29:1019-1023(2011).
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DR   EMBL; CM001266; EHH22630.1; -; Genomic_DNA.
DR   AlphaFoldDB; G7NBY0; -.
DR   Proteomes; UP000013456; Chromosome 14.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0047730; F:carnosine synthase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0035499; P:carnosine biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.50.20; -; 1.
DR   Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR   InterPro; IPR011761; ATP-grasp.
DR   InterPro; IPR041472; BL00235/CARNS1_N.
DR   InterPro; IPR031046; CARNS1.
DR   PANTHER; PTHR48066; CARNOSINE SYNTHASE 1; 1.
DR   PANTHER; PTHR48066:SF1; CARNOSINE SYNTHASE 1; 1.
DR   Pfam; PF18130; ATPgrasp_N; 1.
DR   Pfam; PF15632; ATPgrasp_Ter; 1.
DR   SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR   PROSITE; PS50975; ATP_GRASP; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW   Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00409}.
FT   DOMAIN          400..604
FT                   /note="ATP-grasp"
FT                   /evidence="ECO:0000259|PROSITE:PS50975"
SQ   SEQUENCE   711 AA;  76589 MW;  0225E7EE77F10ADD CRC64;
     MLLCLSPAWL MKVPAPGQPG EAALLVSKAV SFHPGGLTFL DDFVPPRRAT YFLAGLGLGP
     SRGREAAELA RDLTCPTGAS AELARLLEDR LLTRQLLAQQ GGVAVPATLA FTYKPPGLLR
     GGDSSPGLRL VELSGKEGQE TLVREEVEAF LRSEALGDVL QVAVKLSGWR WRGRQALHLH
     PRAELGAVVN TVLALLEKLE EEESVLVEAV YPPVQLPCSD GPSPGPGLAV RICAVVCRTQ
     GDRPLLSKVV CGVGRGDRPL RHHNSLPRTL EVALAQCGLG EEAQVAAVRQ RVKAAAEAAL
     TAQLHLVESD PNHFASQLVQ TFIHFDMTEH RRDEENARLL AELVRARGLK LDGCFSYWDD
     CLVLTALLCQ ELGLPCSPPA AMRLAKKKSL TQLHLLRHHG PPWPAPSLHA VPCCPLESEA
     DVERAVHQVP LPGVMKLEFG AGAVGVRLVE DAPQCHEHFS RITRDLQGEA DHPGIGLGWG
     NAMLLMEFVE GTEHDVDLVL FGGRLLAAFV SDNGPTRLPG FTETAACMPT GLASEQEAQM
     VQAAFRCCLG CGLLDGVFNV ELKLTGAGPR LIEINPRMGG FYLRDWILEL YGVDLLLAAV
     MVACGLRPAL PTRPRARGHL VGVMCLVSQH LQALSSTASR ETLQALHDRG LLRLNLLEEA
     LVPGEYEEPY CSVACAGSSP TEARLRLLGL CQGLGIDGPS YPVAHFLSHF K
//