ID G7P8B5_MACFA Unreviewed; 398 AA.
AC G7P8B5;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=Ion transport domain-containing protein {ECO:0000259|Pfam:PF00520};
GN ORFNames=EGM_15397 {ECO:0000313|EMBL:EHH54536.1};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541;
RN [1] {ECO:0000313|EMBL:EHH54536.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CE-4 {ECO:0000313|EMBL:EHH54536.1};
RX PubMed=22002653; DOI=10.1038/nbt.1992;
RA Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q.,
RA Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z.,
RA Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y.,
RA Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X.,
RA Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W.,
RA Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.;
RT "Genome sequencing and comparison of two nonhuman primate animal models,
RT the cynomolgus and Chinese rhesus macaques.";
RL Nat. Biotechnol. 29:1019-1023(2011).
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DR EMBL; CM001281; EHH54536.1; -; Genomic_DNA.
DR AlphaFoldDB; G7P8B5; -.
DR eggNOG; KOG2302; Eukaryota.
DR OrthoDB; 2911220at2759; -.
DR Proteomes; UP000009130; Chromosome 6.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR47131; CATION CHANNEL SPERM-ASSOCIATED PROTEIN 3; 1.
DR PANTHER; PTHR47131:SF1; CATION CHANNEL SPERM-ASSOCIATED PROTEIN 3; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 54..73
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 112..131
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 174..198
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 210..226
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 246..268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 50..270
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
SQ SEQUENCE 398 AA; 46274 MW; 26BAD9D56C0694A9 CRC64;
MSQHHRQSQS RVLSSSPVDT TSVGFCPIFK KFKRKDDECR AFVKKVIMSR FFKIIMISAV
TSNGFFMALW TSYEIRYRLF RLLELSEIFF VSICTSELSM KLYVDPINYW KNGYNVLDVI
VMIIMLLPYT VRELMGRQFS YVNIADGMQS LRILKLIGYS RGIRTLIIAV GQTVYTVASV
LLLLFLLMYI FAILGFCLFG SADKGDHENW GNLAAAFFTL FSLATVDGWT DLQKQLDNRE
FALSRAFTII FILLASFIFL NMFVGVMIMH TEDSIKKFER ELMLERQVTL MGEKQVILQR
QQEEISRLMH IQENADCKSF SELVENFKKT LHHTDPMVLD DFGTSLPFID IYFSTLDYQD
TTVHKLQELY YEIVHVLGLM LEDLPQEKPQ SLEKVEEK
//
