ID G7PMR1_MACFA Unreviewed; 904 AA.
AC G7PMR1; A0A7N9IE29;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=KAT8 regulatory NSL complex subunit 3 {ECO:0000313|Ensembl:ENSMFAP00000056168.1};
GN Name=KANSL3 {ECO:0000313|Ensembl:ENSMFAP00000056168.1};
GN ORFNames=EGM_05022 {ECO:0000313|EMBL:EHH55756.1};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541;
RN [1] {ECO:0000313|EMBL:EHH55756.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CE-4 {ECO:0000313|EMBL:EHH55756.1};
RX PubMed=22002653; DOI=10.1038/nbt.1992;
RA Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q.,
RA Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z.,
RA Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y.,
RA Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X.,
RA Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W.,
RA Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.;
RT "Genome sequencing and comparison of two nonhuman primate animal models,
RT the cynomolgus and Chinese rhesus macaques.";
RL Nat. Biotechnol. 29:1019-1023(2011).
RN [2] {ECO:0000313|Ensembl:ENSMFAP00000056168.1, ECO:0000313|Proteomes:UP000233100}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSMFAP00000056168.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; CM001288; EHH55756.1; -; Genomic_DNA.
DR RefSeq; XP_005575048.1; XM_005574991.2.
DR RefSeq; XP_005575049.1; XM_005574992.2.
DR RefSeq; XP_005575050.1; XM_005574993.2.
DR RefSeq; XP_015288702.1; XM_015433216.1.
DR ESTHER; macfa-KANSL3; NLS3-Tex30.
DR Ensembl; ENSMFAT00000084052.1; ENSMFAP00000056168.1; ENSMFAG00000036793.2.
DR GeneID; 102123937; -.
DR KEGG; mcf:102123937; -.
DR CTD; 55683; -.
DR eggNOG; KOG3253; Eukaryota.
DR GeneTree; ENSGT00390000007636; -.
DR OrthoDB; 5405548at2759; -.
DR Proteomes; UP000009130; Chromosome 13.
DR Proteomes; UP000233100; Chromosome 13.
DR Bgee; ENSMFAG00000036793; Expressed in skeletal muscle tissue and 13 other cell types or tissues.
DR GO; GO:0044545; C:NSL complex; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0051571; P:positive regulation of histone H3-K4 methylation; IEA:Ensembl.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR046879; KANL3/Tex30_Abhydrolase.
DR InterPro; IPR026555; NSL3/Tex30.
DR PANTHER; PTHR13136:SF16; KAT8 REGULATORY NSL COMPLEX SUBUNIT 3; 1.
DR PANTHER; PTHR13136; TESTIS DEVELOPMENT PROTEIN PRTD; 1.
DR Pfam; PF20408; Abhydrolase_11; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000233100}.
FT DOMAIN 331..454
FT /note="KANL3/Tex30 alpha/beta hydrolase-like"
FT /evidence="ECO:0000259|Pfam:PF20408"
FT REGION 476..563
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 607..678
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 697..722
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 762..784
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 870..904
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 478..507
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 525..563
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 613..628
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 870..898
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 904 AA; 95997 MW; 08C6B428A852FB45 CRC64;
MAHRGGERDF QTSARRMGTS LLFQLSVHER ELDLVFLDHS YAKPWSAHPD ASSARPTRML
FVTPRRQHES TIESDVPIDV ETVMSTPMPL YDNQKARSVM NECERHVIFA RTDADAPPPP
EDWEEHVNRT GWTMAQNKLF NKILKALQSD RLARLANEGA CNEPVLRRVA VDKCARRVRQ
ALASVSWDTK LIQWLHTTLV ETLSLPMLAA YLDALQTLKG KIPTLIDRML VSSNTKTGAA
GAEALSLLLK RPWDPAVGVL SHNKPSKLPG SPLILIASSG PSSSVFPTSR RHRFWQSQLS
CLGKVIPVAT HLLNNGSGVG VLQCLEHMIG AVRSKVLEIH SHFPHKPIIL IGWNTGALVA
CHVSVMEYVT AVVCLGFPLL TVDGPRGDVD DPLLDMKTPV LFVIGQNSLQ CHPEAMEDFR
EKIRAENSLV VVGGADDNLR ISKAKKKSEG LTQSMVDRCI QDEIVDFLTG VLTRAEGHMG
SEPRDQDAEK KKKPRDVARR DLAFEVPERG SRPASPAAKL PASPSGSEDL SSVSSSPTSS
PKTKVTAVTS AQKSSQIGSS QLLKRHVQRT EAVLTHKQAQ AQFAAFLKQN MLVRKALPPG
TSSCLFVPIS SEPPEEGEKE DLRVQLKRHH PSSPLPGSKT SKRPKIKVSL ISQGDTAGGP
CAPSQGSAPE AAGGKPITMT LGQASAGAKE LTGLLTTAKS SSSEGGVSAS PAPSVVSSST
APSALHTLQS RLVATSPGSS LPGATSASSL LQGLSFSLQD ISSKTSGLPA NPSPGPAPQA
TSVKLPTPMQ SLGAITTGTS TIVRTIPVAT TLSSLGATPG GKPTAIHQLL TNGGLAKLAS
SLPGLAQISH QASGLKVPTT ITLTLRGQPS RITTLSPMGS GAAPSEEPSS QVLPSSSQRL
PPAP
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