ID G7PPB4_MACFA Unreviewed; 166 AA.
AC G7PPB4;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=Thy-1 membrane glycoprotein {ECO:0000256|ARBA:ARBA00019731};
DE AltName: Full=Thy-1 antigen {ECO:0000256|ARBA:ARBA00032696};
GN Name=THY1 {ECO:0000313|Ensembl:ENSMFAP00000007248.2};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000007248.2, ECO:0000313|Proteomes:UP000233100};
RN [1] {ECO:0000313|Ensembl:ENSMFAP00000007248.2, ECO:0000313|Proteomes:UP000233100}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSMFAP00000007248.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: May play a role in cell-cell or cell-ligand interactions
CC during synaptogenesis and other events in the brain.
CC {ECO:0000256|ARBA:ARBA00003467}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004609};
CC Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004609}. Membrane
CC {ECO:0000256|ARBA:ARBA00004589}; Lipid-anchor, GPI-anchor
CC {ECO:0000256|ARBA:ARBA00004589}.
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DR AlphaFoldDB; G7PPB4; -.
DR STRING; 9541.ENSMFAP00000007248; -.
DR Ensembl; ENSMFAT00000025937.2; ENSMFAP00000007248.2; ENSMFAG00000041030.2.
DR VEuPathDB; HostDB:ENSMFAG00000041030; -.
DR eggNOG; ENOG502S18P; Eukaryota.
DR GeneTree; ENSGT00390000012352; -.
DR OrthoDB; 5304893at2759; -.
DR Proteomes; UP000233100; Chromosome 14.
DR Bgee; ENSMFAG00000041030; Expressed in temporal lobe and 12 other cell types or tissues.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0098552; C:side of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005178; F:integrin binding; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR GO; GO:0030334; P:regulation of cell migration; IEA:InterPro.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013106; Ig_V-set.
DR InterPro; IPR013151; Immunoglobulin.
DR InterPro; IPR033292; THY1.
DR PANTHER; PTHR19226; THY-1 MEMBRANE GLYCOPROTEIN; 1.
DR PANTHER; PTHR19226:SF2; THY-1 MEMBRANE GLYCOPROTEIN; 1.
DR Pfam; PF00047; ig; 1.
DR SMART; SM00406; IGv; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000233100};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..166
FT /note="Thy-1 membrane glycoprotein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5030172138"
FT DOMAIN 3..121
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 166 AA; 18720 MW; 69F2EE127074BAD3 CRC64;
MNPAISIALL LTVLQVSRGQ KVTSLTACLV DQSLRLDCRH ENTTSSPIQY EFSLTRETKK
HVLFGTVGVP EHTYRSRTNF TSKYNMKVLY LSAFTSKDEG TYTCALHHSG HSPPISSQNV
TTNWSSVRAS ACWLRTPRGC FCSCSPSPFS RPRISCPCDW WGPWRR
//
