ID G7PPN6_MACFA Unreviewed; 214 AA.
AC G7PPN6;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=TIR domain-containing protein {ECO:0000259|PROSITE:PS50104};
DE Flags: Fragment;
GN ORFNames=EGM_06400 {ECO:0000313|EMBL:EHH56905.1};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541;
RN [1] {ECO:0000313|EMBL:EHH56905.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CE-4 {ECO:0000313|EMBL:EHH56905.1};
RX PubMed=22002653; DOI=10.1038/nbt.1992;
RA Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q.,
RA Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z.,
RA Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y.,
RA Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X.,
RA Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W.,
RA Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.;
RT "Genome sequencing and comparison of two nonhuman primate animal models,
RT the cynomolgus and Chinese rhesus macaques.";
RL Nat. Biotechnol. 29:1019-1023(2011).
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DR EMBL; CM001289; EHH56905.1; -; Genomic_DNA.
DR AlphaFoldDB; G7PPN6; -.
DR eggNOG; ENOG502S07Q; Eukaryota.
DR Proteomes; UP000009130; Chromosome 14.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR017279; Tol-interleuk_rcpt_adapt_Tirap.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR PANTHER; PTHR22662; TIRAP; 1.
DR PANTHER; PTHR22662:SF0; TOLL_INTERLEUKIN-1 RECEPTOR DOMAIN-CONTAINING ADAPTER PROTEIN; 1.
DR Pfam; PF13676; TIR_2; 1.
DR PIRSF; PIRSF037750; TIR_Tirap; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
FT DOMAIN 83..212
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT REGION 1..81
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 40..81
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 214
FT /evidence="ECO:0000313|EMBL:EHH56905.1"
SQ SEQUENCE 214 AA; 23331 MW; B7888D06BB09506E CRC64;
MASSTSLPAP GSRPKKPLGK MADWFRQTLL KKPKKRPDSP ESTSSNTSQP ASQDRLSPSL
SLVTSPSLPP THASDSGSSR WSKDYDVCVC HSEEDLVAAQ NLVSYLEGSS TSLRCFLQLR
DATPGGAIVS ELCQALNNSH CRVLLITPGF LQDPWCKYQM LQALTEAPGA EGRTIPLLSG
LSRDAYPPEL RFMYYVDGRG PDGGFRQVKE AVMR
//
