ID G7PV54_MACFA Unreviewed; 546 AA.
AC G7PV54;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHH58253.1};
DE Flags: Fragment;
GN ORFNames=EGM_08057 {ECO:0000313|EMBL:EHH58253.1};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541;
RN [1] {ECO:0000313|EMBL:EHH58253.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CE-4 {ECO:0000313|EMBL:EHH58253.1};
RX PubMed=22002653; DOI=10.1038/nbt.1992;
RA Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q.,
RA Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z.,
RA Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y.,
RA Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X.,
RA Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W.,
RA Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.;
RT "Genome sequencing and comparison of two nonhuman primate animal models,
RT the cynomolgus and Chinese rhesus macaques.";
RL Nat. Biotechnol. 29:1019-1023(2011).
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily. ICAM family.
CC {ECO:0000256|ARBA:ARBA00005925}.
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DR EMBL; CM001291; EHH58253.1; -; Genomic_DNA.
DR AlphaFoldDB; G7PV54; -.
DR eggNOG; ENOG502RZRA; Eukaryota.
DR Proteomes; UP000009130; Chromosome 16.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005178; F:integrin binding; IEA:InterPro.
DR GO; GO:0098609; P:cell-cell adhesion; IEA:InterPro.
DR Gene3D; 2.60.40.10; Immunoglobulins; 4.
DR InterPro; IPR048679; ICAM1_3_5_D2.
DR InterPro; IPR013768; ICAM_N.
DR InterPro; IPR047012; ICAM_VCAM.
DR InterPro; IPR003987; ICAM_VCAM_N.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR13771:SF4; CELL ADHESION MOLECULE TCAM-1; 1.
DR PANTHER; PTHR13771; INTERCELLULAR ADHESION MOLECULE; 1.
DR Pfam; PF21146; ICAM1_3_5_D2; 1.
DR Pfam; PF03921; ICAM_N; 1.
DR PRINTS; PR01472; ICAMVCAM1.
DR SUPFAM; SSF48726; Immunoglobulin; 4.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..546
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003502811"
FT TRANSMEM 486..509
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 22..112
FT /note="Intercellular adhesion molecule N-terminal"
FT /evidence="ECO:0000259|Pfam:PF03921"
FT DOMAIN 220..307
FT /note="Intercellular adhesion molecule 1/3/5 D2"
FT /evidence="ECO:0000259|Pfam:PF21146"
FT NON_TER 546
FT /evidence="ECO:0000313|EMBL:EHH58253.1"
SQ SEQUENCE 546 AA; 60341 MW; 513FBEA2D31B8B3D CRC64;
MKMLLFVVWA LLALILCPGV AEESFEVSVW PNQALVEFGQ SLVVNCSTTC PDPGPSGIET
FLKKTQVGKG PQWKEFLLED VTENSILQCF FSCSGIQKDT SLGITVYQPP EQVILELQPA
WVAVDEAFTV KCHVPSVAPL ESLTLALLQG NQELHRKNFM SLAVASQRAE VIISIRAQRE
NDRCNFSCRA ELDLSLQGGS LFQGSSPIKI LRIFEFSQTP HIWVSSLLEV GMAETVSCEV
ARVFPAKEVI FHMFLEDQEL SSFLSWEGDT AWANATFRAM EAGDQELSCL ASLGPMEQKT
RKLVHSYSFP PPILELKESY PLAGTDINVT CSGHVLTSPS PTLRLQGAPD LPAPGESAWL
LLTAREEDDG RNFSCEASLE VQGQWLMKTT VIQLHVLYKP WLEESRCSGK QTWLEGMEHR
LACVPKGNPA PALVCTWNGV VFDLEVLGRM RLRSGPGGLG WVILVLCDLP NSVFCAWTGL
DEGISSALFV VITVALGVGV ITIALYLSYR PCKVDGRKLL SRQKEEDKEE KSQFTVEEEK
STTHII
//
