ID G7PV58_MACFA Unreviewed; 733 AA.
AC G7PV58;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Ig-like domain-containing protein {ECO:0000259|PROSITE:PS50835};
GN ORFNames=EGM_08061 {ECO:0000313|EMBL:EHH58257.1};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541;
RN [1] {ECO:0000313|EMBL:EHH58257.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CE-4 {ECO:0000313|EMBL:EHH58257.1};
RX PubMed=22002653; DOI=10.1038/nbt.1992;
RA Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q.,
RA Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z.,
RA Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y.,
RA Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X.,
RA Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W.,
RA Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.;
RT "Genome sequencing and comparison of two nonhuman primate animal models,
RT the cynomolgus and Chinese rhesus macaques.";
RL Nat. Biotechnol. 29:1019-1023(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR EMBL; CM001291; EHH58257.1; -; Genomic_DNA.
DR AlphaFoldDB; G7PV58; -.
DR eggNOG; ENOG502QW63; Eukaryota.
DR Proteomes; UP000009130; Chromosome 16.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 4.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR040878; IL-40-like_Ig.
DR InterPro; IPR013151; Immunoglobulin.
DR PANTHER; PTHR11481; IMMUNOGLOBULIN FC RECEPTOR; 1.
DR PANTHER; PTHR11481:SF97; LOW AFFINITY IMMUNOGLOBULIN GAMMA FC REGION RECEPTOR II-A-RELATED; 1.
DR Pfam; PF00047; ig; 1.
DR Pfam; PF13895; Ig_2; 1.
DR Pfam; PF17736; Ig_C17orf99; 1.
DR SMART; SM00409; IG; 5.
DR SMART; SM00408; IGc2; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50835; IG_LIKE; 4.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW IgG-binding protein {ECO:0000256|ARBA:ARBA00022652};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..733
FT /note="Ig-like domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003503038"
FT TRANSMEM 594..615
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 695..712
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 26..112
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 227..306
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 319..392
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 490..582
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 636..662
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 636..651
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 733 AA; 81768 MW; 92A8A7EBF19DAD13 CRC64;
MQPRWARGAT MWLGVLLTLL LSFTINSVDM KSLPDWTVQN GKNLTLQCCA DVSTTSHVKP
QHQMLFYKDD VLFYNISSMK STESYFIPEA RVYDSGTYKC TVIVNNKEKT TSEYQVLVRG
VPSPRVTLDK KEAIQGGVVR VNCSVPEEKA PIHFTIEKLE LNKKMAKQKR EKTSRDQNFV
MLEFPIEEQD SVLSFRCQAR IIAGIHVQTS ESTKSELVTV RESFSTPKFH ISPTGMITEG
AQLHIKCTIQ VTHLAQEFPE IIIQKDKAIV AHSRHGNEAV YSVMAMVEHN GNYTCKVESS
RISKVSSIIV NVTELFSKPE LETSFTRLDQ GERLNLSCSI PGAPPANFTI QKGDTIVSQT
QNFTKIASKG DSGTYICTAG IDKVVKKSNT VQIVVCEMLS QPRISHDAQF EVIKGQTIEV
SCRSINGTSP ISYHLLKTSK ILENSTKNSN DPAVFKDNPT EDVEYQCVAD NCHSHAEMLS
EVLRVKVIAP VDEVQISILS NKVVESGEDI VLQCAVNEGS GPITYRFYRE KEGKPFHQTT
LNATQEFWTK PKASKEQEGE YYCTAFNRAN HASSVPRSKI LTVRVVLAAW KKGLIAVVVI
GVIIAFLIIG AKCYFLRKAK AKQMPVEMSR PAVPLLNSNN EKMSDPSMEA NSHYGHNDDV
GNHAMKPIND NKDISWTQIA APDEELNGQD GRPNYCLLLL LLLLLLLCVY LVKKGTETVY
TEVRKAVPGF PQS
//
