ID G7V846_THELD Unreviewed; 316 AA.
AC G7V846;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=L-threonine 3-dehydrogenase {ECO:0000313|EMBL:AER67377.1};
DE EC=1.1.1.103 {ECO:0000313|EMBL:AER67377.1};
GN OrderedLocusNames=Tlie_1655 {ECO:0000313|EMBL:AER67377.1};
OS Thermovirga lienii (strain ATCC BAA-1197 / DSM 17291 / Cas60314).
OC Bacteria; Synergistota; Synergistia; Synergistales; Thermovirgaceae;
OC Thermovirga.
OX NCBI_TaxID=580340 {ECO:0000313|EMBL:AER67377.1, ECO:0000313|Proteomes:UP000005868};
RN [1] {ECO:0000313|Proteomes:UP000005868}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1197 / DSM 17291 / Cas60314
RC {ECO:0000313|Proteomes:UP000005868};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Peters L., Mikhailova N., Saunders E.,
RA Kyrpides N., Mavromatis K., Ivanova N., Last F.I., Brettin T., Detter J.C.,
RA Han C., Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F.,
RA Hugenholtz P., Woyke T., Wu D., Spring S., Schroeder M., Brambilla E.-M.,
RA Klenk H.-P., Eisen J.A.;
RT "The complete genome of chromosome of Thermovirga lienii DSM 17291.";
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AER67377.1, ECO:0000313|Proteomes:UP000005868}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1197 / DSM 17291 / Cas60314
RC {ECO:0000313|Proteomes:UP000005868};
RX PubMed=22768366; DOI=10.4056/sigs.2726028;
RA Goker M., Saunders E., Lapidus A., Nolan M., Lucas S., Hammon N.,
RA Deshpande S., Cheng J.F., Han C., Tapia R., Goodwin L.A., Pitluck S.,
RA Liolios K., Mavromatis K., Pagani I., Ivanova N., Mikhailova N., Pati A.,
RA Chen A., Palaniappan K., Land M., Chang Y.J., Jeffries C.D.,
RA Brambilla E.M., Rohde M., Spring S., Detter J.C., Woyke T., Bristow J.,
RA Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT "Genome sequence of the moderately thermophilic, amino-acid-degrading and
RT sulfur-reducing bacterium Thermovirga lienii type strain (Cas60314(T)).";
RL Stand. Genomic Sci. 6:230-239(2012).
CC -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC family. {ECO:0000256|ARBA:ARBA00007637}.
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DR EMBL; CP003096; AER67377.1; -; Genomic_DNA.
DR RefSeq; WP_014163785.1; NC_016148.1.
DR AlphaFoldDB; G7V846; -.
DR STRING; 580340.Tlie_1655; -.
DR KEGG; tli:Tlie_1655; -.
DR eggNOG; COG0451; Bacteria.
DR HOGENOM; CLU_007383_19_1_0; -.
DR OrthoDB; 9779902at2; -.
DR Proteomes; UP000005868; Chromosome.
DR GO; GO:0008743; F:L-threonine 3-dehydrogenase activity; IEA:UniProtKB-EC.
DR CDD; cd05272; TDH_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR001509; Epimerase_deHydtase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR42687; L-THREONINE 3-DEHYDROGENASE; 1.
DR PANTHER; PTHR42687:SF1; L-THREONINE 3-DEHYDROGENASE, MITOCHONDRIAL; 1.
DR Pfam; PF01370; Epimerase; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000313|EMBL:AER67377.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000005868}.
FT DOMAIN 4..240
FT /note="NAD-dependent epimerase/dehydratase"
FT /evidence="ECO:0000259|Pfam:PF01370"
SQ SEQUENCE 316 AA; 35340 MW; 654860802FBAF3F4 CRC64;
MKRILVSGGA GQIGSELVPA LRERYGADNV ICGDIKIPQG SLAEDGPFVQ LDCLDEEKVI
ETIKKFNVGT IYHLPALLSA TAERNPQKAW NINMNGLLIA LEAAREFKCS IFVPSSIAAF
GPSTPRVKTP QDTIQRPQTI YGITKVAGEL LCDYYFIKWG VDARGVRYPG IISYKTPPGG
GTTDYAVDIF YGAIKEKRYE CFLREDTRLD MMYMPDAVKA AISLMEADPS KLVHRNAFNI
TAMSFTPHEL AQEIKKHIPD FVISYSVDPL RQSIADTWPD SLDDTCAREE WGWSPDYDIS
QMTKDMLENL KKKLLN
//
