ID G7VAF2_THELD Unreviewed; 503 AA.
AC G7VAF2;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Succinate CoA transferase {ECO:0000313|EMBL:AER67602.1};
DE EC=3.1.2.1 {ECO:0000313|EMBL:AER67602.1};
GN OrderedLocusNames=Tlie_1893 {ECO:0000313|EMBL:AER67602.1};
OS Thermovirga lienii (strain ATCC BAA-1197 / DSM 17291 / Cas60314).
OG Plasmid pTLIE01 {ECO:0000313|EMBL:AER67602.1,
OG ECO:0000313|Proteomes:UP000005868}.
OC Bacteria; Synergistota; Synergistia; Synergistales; Thermovirgaceae;
OC Thermovirga.
OX NCBI_TaxID=580340 {ECO:0000313|EMBL:AER67602.1, ECO:0000313|Proteomes:UP000005868};
RN [1] {ECO:0000313|EMBL:AER67602.1, ECO:0000313|Proteomes:UP000005868}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1197 / DSM 17291 / Cas60314
RC {ECO:0000313|Proteomes:UP000005868};
RC PLASMID=Plasmid pTLIE01 {ECO:0000313|Proteomes:UP000005868};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Peters L., Mikhailova N., Saunders E.,
RA Kyrpides N., Mavromatis K., Ivanova N., Last F.I., Brettin T., Detter J.C.,
RA Han C., Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F.,
RA Hugenholtz P., Woyke T., Wu D., Spring S., Schroeder M., Brambilla E.-M.,
RA Klenk H.-P., Eisen J.A.;
RT "The complete genome of plasmid of Thermovirga lienii DSM 17291.";
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the acetyl-CoA hydrolase/transferase family.
CC {ECO:0000256|ARBA:ARBA00009632}.
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DR EMBL; CP003097; AER67602.1; -; Genomic_DNA.
DR RefSeq; WP_014164005.1; NC_016149.1.
DR AlphaFoldDB; G7VAF2; -.
DR KEGG; tli:Tlie_1893; -.
DR eggNOG; COG0427; Bacteria.
DR HOGENOM; CLU_019748_3_0_0; -.
DR OrthoDB; 9801795at2; -.
DR Proteomes; UP000005868; Plasmid pTLIE01.
DR GO; GO:0008775; F:acetate CoA-transferase activity; IEA:InterPro.
DR GO; GO:0003986; F:acetyl-CoA hydrolase activity; IEA:UniProtKB-EC.
DR GO; GO:0006083; P:acetate metabolic process; IEA:InterPro.
DR GO; GO:0006084; P:acetyl-CoA metabolic process; IEA:InterPro.
DR Gene3D; 3.30.750.70; 4-hydroxybutyrate coenzyme like domains; 1.
DR Gene3D; 3.40.1080.20; Acetyl-CoA hydrolase/transferase C-terminal domain; 1.
DR Gene3D; 3.40.1080.10; Glutaconate Coenzyme A-transferase; 1.
DR InterPro; IPR026888; AcetylCoA_hyd_C.
DR InterPro; IPR038460; AcetylCoA_hyd_C_sf.
DR InterPro; IPR046433; ActCoA_hydro.
DR InterPro; IPR003702; ActCoA_hydro_N.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR InterPro; IPR017821; Succinate_CoA_transferase.
DR NCBIfam; TIGR03458; YgfH_subfam; 1.
DR PANTHER; PTHR43609; ACETYL-COA HYDROLASE; 1.
DR PANTHER; PTHR43609:SF1; ACETYL-COA HYDROLASE; 1.
DR Pfam; PF13336; AcetylCoA_hyd_C; 1.
DR Pfam; PF02550; AcetylCoA_hydro; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 2.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:AER67602.1};
KW Plasmid {ECO:0000313|EMBL:AER67602.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000005868};
KW Transferase {ECO:0000313|EMBL:AER67602.1}.
FT DOMAIN 12..217
FT /note="Acetyl-CoA hydrolase/transferase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02550"
FT DOMAIN 322..465
FT /note="Acetyl-CoA hydrolase/transferase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13336"
FT ACT_SITE 290
FT /note="5-glutamyl coenzyme A thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-1"
FT BINDING 265..269
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 360
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 380
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 384
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 404
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
SQ SEQUENCE 503 AA; 55853 MW; 33F6D02C32942951 CRC64;
MELHERIRSK VLREKVVSKE EAAKFIKDGM TVACSGFTPA GYPKVVPEMI AQRAQKGENI
RLNIITGAST GDELDGVLAR SGVIKKRYPY QTNTDCRNGI NSGQIDFCDI HLSHLPQFIK
LGYLGNIDIA LVEAVAITED GGIVPSTSVG ATNTFVQKAD KVIVEINFAQ PLDLEGLHDI
YDPGDPPLRS PIPLCRVSDR IGIPYIPCPK EKIVAIVISN RKDSTNPVAE IDRDSRLIAG
HIIDFLEFEI KKGRFPKNLL PLQSGVGSVA NAVLTNFKES RFENLEIYSE VLQDAVLELI
DTGKVSFASG TAFTISPSKL DHFYKNLKFY KNYTILRPQE ISNNPEVIRR LGVIAMNTAI
EIDIYGNVNS THIGGCAMMN GIGGSGDFTR NAALSIFTTK SVAKDGNISS IVPMVSHHDH
TEHDVHVVVT EQGLADLRGL SPKERVKQII GKCAHPDFRK ELWDYYRKAL FYAKYKHTPH
MLNRVFDLHN YMVKYGTMKP KVC
//
