ID   G7X8I9_ASPKW            Unreviewed;       356 AA.
AC   G7X8I9;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   SubName: Full=Zinc-binding dehydrogenase family oxidoreductase {ECO:0000313|EMBL:GAA83289.1};
GN   ORFNames=AKAW_01404 {ECO:0000313|EMBL:GAA83289.1};
OS   Aspergillus kawachii (strain NBRC 4308) (White koji mold) (Aspergillus
OS   awamori var. kawachi).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=1033177 {ECO:0000313|EMBL:GAA83289.1};
RN   [1] {ECO:0000313|EMBL:GAA83289.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IFO 4308 {ECO:0000313|EMBL:GAA83289.1};
RX   PubMed=22045919; DOI=10.1128/EC.05224-11;
RA   Futagami T., Mori K., Yamashita A., Wada S., Kajiwara Y., Takashita H.,
RA   Omori T., Takegawa K., Tashiro K., Kuhara S., Goto M.;
RT   "Genome sequence of the white koji mold Aspergillus kawachii IFO 4308, used
RT   for brewing the Japanese distilled spirit shochu.";
RL   Eukaryot. Cell 10:1586-1587(2011).
CC   -!- SUBUNIT: Monomer. {ECO:0000256|ARBA:ARBA00011245}.
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. {ECO:0000256|ARBA:ARBA00008072}.
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DR   EMBL; DF126449; GAA83289.1; -; Genomic_DNA.
DR   AlphaFoldDB; G7X8I9; -.
DR   STRING; 1033177.G7X8I9; -.
DR   VEuPathDB; FungiDB:AKAW_01404; -.
DR   eggNOG; KOG1198; Eukaryota.
DR   InParanoid; G7X8I9; -.
DR   Proteomes; UP000006812; Unassembled WGS sequence.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0016651; F:oxidoreductase activity, acting on NAD(P)H; IEA:InterPro.
DR   CDD; cd08249; enoyl_reductase_like; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   InterPro; IPR047122; Trans-enoyl_RdTase-like.
DR   PANTHER; PTHR45348; HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG); 1.
DR   PANTHER; PTHR45348:SF1; TRANS-ENOYL REDUCTASE STHE; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          17..353
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   356 AA;  38467 MW;  5BC7A1580675730C CRC64;
     MSGLPSNQTA IVALDDGTLA LRDGIPIPSL EDDMILVKNA FVALNPIDTK MVGKLASPGA
     IAGMDFAGEV IRIGSNVRTS ASIKPGDQVC GAVPGMHCLT PSVGAFAQYV GATDLTVLKV
     PNHMSLEQAA TLGSGVGTVG LALFKSLNVP GWPGLPAEKP VDVLVYGGST ATGTLAIQFL
     KLSGMNVITT CSPRNYDLVR SFGAAAYFDY HQETCVDEIR KYTRNSLKFV LDCISEPETM
     QFCYKCLGRS GGKYTALEPY PEFLHTRPKT VEPDWVLGPM VMGKRLGWPE PFGGEGIEEY
     REFGFKWFKQ VQELLDEGKL KTHPYRIVGN SLAETLGGLR LLEEKQVSGQ KLVCRV
//