ID G7XDF8_ASPKW Unreviewed; 389 AA.
AC G7XDF8;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE RecName: Full=D-xylose 1-dehydrogenase (NADP(+), D-xylono-1,5-lactone-forming) {ECO:0000256|ARBA:ARBA00038984};
DE EC=1.1.1.179 {ECO:0000256|ARBA:ARBA00038984};
DE AltName: Full=D-xylose-NADP dehydrogenase {ECO:0000256|ARBA:ARBA00042988};
GN ORFNames=AKAW_02795 {ECO:0000313|EMBL:GAA84681.1};
OS Aspergillus kawachii (strain NBRC 4308) (White koji mold) (Aspergillus
OS awamori var. kawachi).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=1033177 {ECO:0000313|EMBL:GAA84681.1};
RN [1] {ECO:0000313|EMBL:GAA84681.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IFO 4308 {ECO:0000313|EMBL:GAA84681.1};
RX PubMed=22045919; DOI=10.1128/EC.05224-11;
RA Futagami T., Mori K., Yamashita A., Wada S., Kajiwara Y., Takashita H.,
RA Omori T., Takegawa K., Tashiro K., Kuhara S., Goto M.;
RT "Genome sequence of the white koji mold Aspergillus kawachii IFO 4308, used
RT for brewing the Japanese distilled spirit shochu.";
RL Eukaryot. Cell 10:1586-1587(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=D-xylose + NADP(+) = D-xylono-1,5-lactone + H(+) + NADPH;
CC Xref=Rhea:RHEA:22000, ChEBI:CHEBI:15378, ChEBI:CHEBI:15867,
CC ChEBI:CHEBI:53455, ChEBI:CHEBI:57783, ChEBI:CHEBI:58349;
CC EC=1.1.1.179; Evidence={ECO:0000256|ARBA:ARBA00036678};
CC -!- SIMILARITY: Belongs to the Gfo/Idh/MocA family.
CC {ECO:0000256|ARBA:ARBA00010928}.
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DR EMBL; DF126452; GAA84681.1; -; Genomic_DNA.
DR AlphaFoldDB; G7XDF8; -.
DR STRING; 1033177.G7XDF8; -.
DR VEuPathDB; FungiDB:AKAW_02795; -.
DR eggNOG; KOG2741; Eukaryota.
DR InParanoid; G7XDF8; -.
DR Proteomes; UP000006812; Unassembled WGS sequence.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR000683; Gfo/Idh/MocA-like_OxRdtase_N.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR22604:SF115; DIHYDRODIOL DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G07520)-RELATED; 1.
DR PANTHER; PTHR22604; OXIDOREDUCTASES; 1.
DR Pfam; PF01408; GFO_IDH_MocA; 1.
DR SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
FT DOMAIN 12..140
FT /note="Gfo/Idh/MocA-like oxidoreductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01408"
SQ SEQUENCE 389 AA; 42058 MW; A153FE31EE7580CB CRC64;
MSSHSVPVPF GLRWGIIATG SIAETFAKDL LIHPASRGVT DVSHLLVAVA SSRSTEIASR
FINKVGAPSS CIAYGSYDAL VADPRVDVVY VASPHSHHYQ NAMLGLQAGK HVLCEKPFTA
TARQAHRLVE TARARNLFLM EAMWTRFLPI SAQIREEVQN GAIGPVIRIF ADNSIGTNAL
KELKDSYLTK KDLAGGALLD LGVYPVHWIM QTLAPSPDPK PSSILSAITP LLGAGVDEST
TIIMTFPGTS PSPVSVQAIA SSSLRAMADP DGHTPVVRIQ GDSGEIQIYG PPWCPSKYRI
IKRVQQFGIT GGGEDFEYRV PGGAHGLCFE ADEVARCVRD ERLESATMPW TESLTVIEIL
DAVRRAHGLC FSEIVESEEY PVIMPAKMN
//
