ID   G7XVN7_ASPKW            Unreviewed;       414 AA.
AC   G7XVN7;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   SubName: Full=Saccharopine dehydrogenase {ECO:0000313|EMBL:GAA90996.1};
GN   ORFNames=AKAW_09110 {ECO:0000313|EMBL:GAA90996.1};
OS   Aspergillus kawachii (strain NBRC 4308) (White koji mold) (Aspergillus
OS   awamori var. kawachi).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=1033177 {ECO:0000313|EMBL:GAA90996.1};
RN   [1] {ECO:0000313|EMBL:GAA90996.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IFO 4308 {ECO:0000313|EMBL:GAA90996.1};
RX   PubMed=22045919; DOI=10.1128/EC.05224-11;
RA   Futagami T., Mori K., Yamashita A., Wada S., Kajiwara Y., Takashita H.,
RA   Omori T., Takegawa K., Tashiro K., Kuhara S., Goto M.;
RT   "Genome sequence of the white koji mold Aspergillus kawachii IFO 4308, used
RT   for brewing the Japanese distilled spirit shochu.";
RL   Eukaryot. Cell 10:1586-1587(2011).
CC   -!- SIMILARITY: Belongs to the saccharopine dehydrogenase family.
CC       {ECO:0000256|ARBA:ARBA00038048}.
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DR   EMBL; DF126477; GAA90996.1; -; Genomic_DNA.
DR   AlphaFoldDB; G7XVN7; -.
DR   VEuPathDB; FungiDB:AKAW_09110; -.
DR   eggNOG; KOG2733; Eukaryota.
DR   InParanoid; G7XVN7; -.
DR   Proteomes; UP000006812; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR005097; Sacchrp_dh_NADP.
DR   PANTHER; PTHR12286:SF5; SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE; 1.
DR   PANTHER; PTHR12286; UNCHARACTERIZED; 1.
DR   Pfam; PF03435; Sacchrp_dh_NADP; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        281..300
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          10..139
FT                   /note="Saccharopine dehydrogenase NADP binding"
FT                   /evidence="ECO:0000259|Pfam:PF03435"
SQ   SEQUENCE   414 AA;  45935 MW;  41DB7CCD70E1B353 CRC64;
     MESNKQYDLI VLGPTGYTGR FCADHIVKNF PTNLKWALAG RSLSKLENIA KELKNVNPDR
     AEPDLLAVQL NREELHPLVQ KTRVIINCVG PYCLYSTPVI EACASNGTHY VDATGETHWV
     KEIIGEYHET AKANGAVIIP CVGIESAPAD LLAWATVKRV REDLSCHTRS ITGDIHEIKS
     SGASGGTLST VLTFFENVPP SEMRKISTPF ALAASAPPKD IPREPLWARL LGIRSVRDMG
     ILTTSPSGLA DTTTVHRSST LMPEFYGPRF YFRQFLRARN AFTGILWHYT FLFAITALLL
     PPVRTLVRKY IYTPGTGPTL EDSVNDFVEY RAVATADQDT PTPQRVLGKL RYQGTMYEFT
     GLSLAEAAMT ILENEEKVKK VSRCGIVTTA TLGQEFIDRW DKVGCHIETQ IVDN
//