ID   G7XWE4_ASPKW            Unreviewed;       345 AA.
AC   G7XWE4;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   27-MAR-2024, entry version 43.
DE   RecName: Full=Enoyl reductase (ER) domain-containing protein {ECO:0000259|SMART:SM00829};
GN   ORFNames=AKAW_09367 {ECO:0000313|EMBL:GAA91253.1};
OS   Aspergillus kawachii (strain NBRC 4308) (White koji mold) (Aspergillus
OS   awamori var. kawachi).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=1033177 {ECO:0000313|EMBL:GAA91253.1};
RN   [1] {ECO:0000313|EMBL:GAA91253.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IFO 4308 {ECO:0000313|EMBL:GAA91253.1};
RX   PubMed=22045919; DOI=10.1128/EC.05224-11;
RA   Futagami T., Mori K., Yamashita A., Wada S., Kajiwara Y., Takashita H.,
RA   Omori T., Takegawa K., Tashiro K., Kuhara S., Goto M.;
RT   "Genome sequence of the white koji mold Aspergillus kawachii IFO 4308, used
RT   for brewing the Japanese distilled spirit shochu.";
RL   Eukaryot. Cell 10:1586-1587(2011).
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. {ECO:0000256|ARBA:ARBA00008072}.
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DR   EMBL; DF126479; GAA91253.1; -; Genomic_DNA.
DR   AlphaFoldDB; G7XWE4; -.
DR   STRING; 1033177.G7XWE4; -.
DR   VEuPathDB; FungiDB:AKAW_09367; -.
DR   eggNOG; KOG1198; Eukaryota.
DR   InParanoid; G7XWE4; -.
DR   Proteomes; UP000006812; Unassembled WGS sequence.
DR   GO; GO:0016651; F:oxidoreductase activity, acting on NAD(P)H; IEA:InterPro.
DR   CDD; cd08249; enoyl_reductase_like; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   InterPro; IPR047122; Trans-enoyl_RdTase-like.
DR   PANTHER; PTHR45348; HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG); 1.
DR   PANTHER; PTHR45348:SF2; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C2E1P3.01; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          8..338
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   345 AA;  37105 MW;  CB1583CE25BC970C CRC64;
     MVKAIAVTAP ETISVVSDWP KPTLRHDCIL VKVVSVALNP TDWKSALRST PIVTVGCDYA
     GIVVDVGPAV TKPFRAGDRV FGVIRGCNPN LPYNGAFSEY ILAPGDLQCA IPENLSFQEA
     ATLGVGMGTI AQSLYQSLQL APFDHPLAQP EPILVYGGAT ATGTLAIQFA KLSGYEVITT
     CSPETEELVK SRGADHVFDY KDPEAADKIR DVTQDRLKLV LDTISTDETA AFCGRAMSSQ
     GGDYTAMIDS KVPRADVRSR WTLGYTVFGE ELTFRGVRIP ASLEDRTFAS EWMEKAAKLL
     ADGRVVPHPV KLGSGGLQGV IEGLKLLKEG KVRGCKLVYN VDEIA
//