ID G7YF92_CLOSI Unreviewed; 535 AA.
AC G7YF92;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Solute carrier family 29 (Equilibrative nucleoside transporter) member 1/2/3 {ECO:0000313|EMBL:GAA51625.1};
GN ORFNames=CLF_106490 {ECO:0000313|EMBL:GAA51625.1};
OS Clonorchis sinensis (Chinese liver fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Opisthorchiida; Opisthorchiata; Opisthorchiidae; Clonorchis.
OX NCBI_TaxID=79923 {ECO:0000313|EMBL:GAA51625.1, ECO:0000313|Proteomes:UP000008909};
RN [1] {ECO:0000313|EMBL:GAA51625.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Henan {ECO:0000313|EMBL:GAA51625.1};
RX PubMed=22023798; DOI=10.1186/gb-2011-12-10-r107;
RA Wang X., Chen W., Huang Y., Sun J., Men J., Liu H., Luo F., Guo L., Lv X.,
RA Deng C., Zhou C., Fan Y., Li X., Huang L., Hu Y., Liang C., Hu X., Xu J.,
RA Yu X.;
RT "The draft genome of the carcinogenic human liver fluke Clonorchis
RT sinensis.";
RL Genome Biol. 12:R107-R107(2011).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Henan;
RA Wang X., Huang Y., Chen W., Liu H., Guo L., Chen Y., Luo F., Zhou W.,
RA Sun J., Mao Q., Liang P., Zhou C., Tian Y., Men J., Lv X., Huang L.,
RA Zhou J., Hu Y., Li R., Zhang F., Lei H., Li X., Hu X., Liang C., Xu J.,
RA Wu Z., Yu X.;
RT "The genome and transcriptome sequence of Clonorchis sinensis provide
RT insights into the carcinogenic liver fluke.";
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
CC {ECO:0000256|ARBA:ARBA00007965}.
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DR EMBL; DF143177; GAA51625.1; -; Genomic_DNA.
DR AlphaFoldDB; G7YF92; -.
DR Proteomes; UP000008909; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005337; F:nucleoside transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR002259; Eqnu_transpt.
DR PANTHER; PTHR10332; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER; 1.
DR PANTHER; PTHR10332:SF10; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 1, ISOFORM A; 1.
DR Pfam; PF01733; Nucleoside_tran; 1.
DR PRINTS; PR01130; DERENTRNSPRT.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008909};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 175..196
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 244..265
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 329..351
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 363..382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 13..32
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 535 AA; 60084 MW; F796A567C3FC1A1D CRC64;
MDSKKESIGI RNTKNKRYAT NQSNNREADH DATQITSGPA RIQVRFSSMA NQVTAQKLLF
AQREGLPTQQ RTEAVTSVVT KRLQISCQAR QAAQRSPDEI PNTITPGLPV FQHITGANLG
TTGNGRCACS TKRVAGVRAH QSSRETLPGG RTGPPYEVLI PHACYHICKV KNNQAILIAV
CAIINNFSYQ IFYLVVRKAR PIKQLSHFEQ ANSKPPLEKA LAGVLAALAQ IASLAGASNF
TTSAFAYFLI ALAILGTSTI MTLMLRRNAH FKSYWNVETC IKVNDTKTQD TEENFLRLSE
LRSETVLESD QPHVTQRSSR HLLKSLYEMW IHGGCTMLTL MYTLMLFPAL LQPIKSVHFS
PDNAWSSVFF VPVIVFLSFN VFDWIGRTLA GFVKWNTSEL TTRLLAQKGI VVAHKPNATL
RKLISRPKGN QDKTKRNNVL YQINCNKFYV GQTGRKLCTR IKEHNAAVRR HDLLSLISIH
EDQEGHIFNL ENAKILAHGN TRHERDFLEA WYSMAGSINR QTELDPIYTP LRAKD
//
