ID G7YMW8_CLOSI Unreviewed; 595 AA.
AC G7YMW8;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=26S proteasome regulatory subunit T4 {ECO:0000313|EMBL:GAA54299.1};
DE Flags: Fragment;
GN ORFNames=CLF_113610 {ECO:0000313|EMBL:GAA54299.1};
OS Clonorchis sinensis (Chinese liver fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Opisthorchiida; Opisthorchiata; Opisthorchiidae; Clonorchis.
OX NCBI_TaxID=79923 {ECO:0000313|EMBL:GAA54299.1, ECO:0000313|Proteomes:UP000008909};
RN [1] {ECO:0000313|EMBL:GAA54299.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Henan {ECO:0000313|EMBL:GAA54299.1};
RX PubMed=22023798; DOI=10.1186/gb-2011-12-10-r107;
RA Wang X., Chen W., Huang Y., Sun J., Men J., Liu H., Luo F., Guo L., Lv X.,
RA Deng C., Zhou C., Fan Y., Li X., Huang L., Hu Y., Liang C., Hu X., Xu J.,
RA Yu X.;
RT "The draft genome of the carcinogenic human liver fluke Clonorchis
RT sinensis.";
RL Genome Biol. 12:R107-R107(2011).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Henan;
RA Wang X., Huang Y., Chen W., Liu H., Guo L., Chen Y., Luo F., Zhou W.,
RA Sun J., Mao Q., Liang P., Zhou C., Tian Y., Men J., Lv X., Huang L.,
RA Zhou J., Hu Y., Li R., Zhang F., Lei H., Li X., Hu X., Liang C., Xu J.,
RA Wu Z., Yu X.;
RT "The genome and transcriptome sequence of Clonorchis sinensis provide
RT insights into the carcinogenic liver fluke.";
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the AAA ATPase family.
CC {ECO:0000256|ARBA:ARBA00006914, ECO:0000256|RuleBase:RU003651}.
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DR EMBL; DF143881; GAA54299.1; -; Genomic_DNA.
DR AlphaFoldDB; G7YMW8; -.
DR Proteomes; UP000008909; Unassembled WGS sequence.
DR GO; GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd19502; RecA-like_PAN_like; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041569; AAA_lid_3.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR003960; ATPase_AAA_CS.
DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032501; Prot_ATP_ID_OB_2nd.
DR PANTHER; PTHR23073; 26S PROTEASOME REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR23073:SF155; 26S PROTEASOME REGULATORY SUBUNIT 10B; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF17862; AAA_lid_3; 1.
DR Pfam; PF14529; Exo_endo_phos_2; 1.
DR Pfam; PF16450; Prot_ATP_ID_OB_C; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF56219; DNase I-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00674; AAA; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU003651};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU003651};
KW Proteasome {ECO:0000256|ARBA:ARBA00022942, ECO:0000313|EMBL:GAA54299.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008909}.
FT DOMAIN 372..511
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT COILED 225..259
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:GAA54299.1"
SQ SEQUENCE 595 AA; 66730 MW; 90BDE7E95C6C43D2 CRC64;
PSSPPEDDHF LIRTLGQLSS SYHFTHLLLV GDFNAPKAPW TELQCVGSSG PFAAALTEVV
QQSAWTQHVV APTRYRAGQQ PSLLDLVITN ERHFVDQVTI NAPLGHSDHC VLTFDFICYW
ARNPEPQTWI RNFCRADFSG MRIFLNQGAY VRPLLEYANP VVYSGRTEDL ILIGRVQRAA
TKIVAGLKSM NCETRLAEGQ TPVSNTAESA REKNLNYYRR KLIEHREIDA RLKEAREKAK
AVTKEYEKAE DDLKALQSVG QVVGDVLKQL TEDHFIVKAS NGPRYVVGCR RSLQTSKLKA
GTRVALDMTT LTIMRQLPRE VDPLVHNMSA EDPGDVSYHS VGGLAEQIRE LREVIELPLM
NPELFIRVGI TPPKGCLLYG PPGTGKTLLA RAVASQLDAN FLKVVSSSIV DKYIGESARL
IREMFNYARD HQPCIIFMDE IDAIGGRRFS EGTSADREIQ RTLMELLNQM DGFDALGQVK
MIMATNRPDT LDPALLRPGR LDRKIEIPLP NEQARMDIMK IHSAPIAKHG EIDWEAVVKL
SDGFNGADLR NVCTEAGMFA IRAERDYTVE EDFMKAVRKI SDAKKLETKL DYKPV
//
